Evidence map›Paper›PMID 37773700›Full record

ArticleImmunity, inflammation and disease2023

CD4

Jue Wang, Lu Pei, Ting Zhao, Xiaoli Liu, Quanrong Wang, Shiyu Zhang, Jubo Li, Hongwei Wu, Dongsheng Niu

Open access · goldAbstract read
In one paragraph

Article in Immunity, inflammation and disease, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. [Expression and clinical significance of lymphocyte subsets in infectious pneumonia and immune-related interstitial lung disease].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2026
    Article
  3. Characteristics of CD4Journal of intensive medicine · 2026
    Article
  4. Preoperative PD-1Oncology letters · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. CD4Immunity, inflammation and disease · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Jue WangJincheng People's Hospital, Jincheng, China.
Lu PeiJincheng People's Hospital, Jincheng, China.
Ting ZhaoJincheng People's Hospital, Jincheng, China.
Xiaoli LiuJincheng People's Hospital, Jincheng, China.
Quanrong WangCritical Medicine Department of Huangpi District People's Hospital Affiliated to Jianghan University, Wuhan, China.
Shiyu ZhangJincheng People's Hospital, Jincheng, China.
Jubo LiJincheng People's Hospital, Jincheng, China.
Hongwei WuJincheng People's Hospital, Jincheng, China.
Dongsheng NiuJincheng People's Hospital, Jincheng, China.ORCID 0000-0003-0245-2820
Changzhi Medical College · CNJianghan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundsElderly and frailty individuals show a more senescent immune system, which may relate to worse outcome in community-acquired pneumonia (CAP). This study aimed to explore prognostic factors related to immune.

methodsSixty of elderly (≥65 years) and frailty (clinical frailty scale ≥5 scores) nonsevere CAP patients and 60 severe CAP (SCAP) patients were recruited at our center. Clinical and laboratory data, and several assessment scores were collected.

resultsCompared with nonsevere CAP group, the elderly and frailty SCAP patients showed higher level of BMI, PaCO2 and lactate in arterial blood-gas, CURB-65 score, ICU admission, mechanical ventilation, shock accidence, and longer hospital stay using two-tailed t test. The SCAP group also showed increased CRP, IL-6, and PCT, and decreased CD3

conclusionsCD4

Indexed as

FrailtyPneumoniaAgedCD4-Positive T-LymphocytesCD8-Positive T-LymphocytesHumansInterleukin-6Lactic AcidPatient AcuityPrognosisRetrospective StudiesInterleukin-6Lactic AcidCD4+ T cellselderly patientsfrailty patientsPCTsevere community-acquired pneumonia (SCAP)

Identifiers

PMID37773700
PMCPMC10540148
OpenAlexW4387166160

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.