Evidence map›Paper›PMID 37773612›Full record

ArticleeLife2023

The chemorepellent, SLIT2, bolsters innate immunity against

Vikrant K Bhosle, Chunxiang Sun, Sajedabanu Patel, Tse Wing Winnie Ho, Johannes Westman, Dustin A Ammendolia, Fatemeh Mirshafiei Langari, Noah Fine, Nicole Toepfner, Zhubing Li and 9 more

Open access · goldAbstract read
In one paragraph

Article in eLife, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 4 institutions in 4 countries.

Vikrant K BhosleCell Biology Program, The Hospital for Sick Children Research Institute, Toronto, Canada.ORCID 0000-0002-2103-6454
Chunxiang SunFaculty of Dentistry, University of Toronto, Toronto, Canada.
Sajedabanu PatelCell Biology Program, The Hospital for Sick Children Research Institute, Toronto, Canada.
Tse Wing Winnie HoThe Keenan Research Centre for Biomedical Science, Unity Health Toronto, Toronto, Canada.ORCID 0000-0003-4465-7859
Johannes WestmanCell Biology Program, The Hospital for Sick Children Research Institute, Toronto, Canada.
Dustin A AmmendoliaCell Biology Program, The Hospital for Sick Children Research Institute, Toronto, Canada.
Fatemeh Mirshafiei LangariProgram in Molecular Medicine, The Hospital for Sick Children Research Institute, Toronto, Canada.
Noah FineFaculty of Dentistry, University of Toronto, Toronto, Canada.
Nicole ToepfnerDepartment of Pediatrics, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
Zhubing LiCell Biology Program, The Hospital for Sick Children Research Institute, Toronto, Canada.
Manraj SharmaCell Biology Program, The Hospital for Sick Children Research Institute, Toronto, Canada.
Judah GlogauerCell Biology Program, The Hospital for Sick Children Research Institute, Toronto, Canada.
Mariana I CapurroCell Biology Program, The Hospital for Sick Children Research Institute, Toronto, Canada.
Nicola L JonesCell Biology Program, The Hospital for Sick Children Research Institute, Toronto, Canada.
Jason T MaynesProgram in Molecular Medicine, The Hospital for Sick Children Research Institute, Toronto, Canada.ORCID 0000-0002-2050-3620
Warren L LeeThe Keenan Research Centre for Biomedical Science, Unity Health Toronto, Toronto, Canada.
Michael GlogauerFaculty of Dentistry, University of Toronto, Toronto, Canada.
Sergio GrinsteinCell Biology Program, The Hospital for Sick Children Research Institute, Toronto, Canada.ORCID 0000-0002-0795-4160
Lisa A RobinsonCell Biology Program, The Hospital for Sick Children Research Institute, Toronto, Canada.ORCID 0000-0003-1714-1929
University of Toronto · CAGreat Ormond Street Hospital · GBUniversity Health Network · CAUniversity Hospital Carl Gustav Carus · DE

Funding

CIHR OV2 170656CIHR PJT-169167
6 · The paper itself

Abstract

Neutrophils are essential for host defense against

Indexed as

Staphylococcal InfectionsStaphylococcus aureusAnimalsChemotaxis, LeukocyteHumansImmunity, InnateMiceNeutrophilsSlit Homolog 2 ProteinSlit Homolog 2 Proteincell biologyhumaninfectious diseaseLL-37microbiologymouseneutrophilsp38 MAPKROBO1SLIT2staphylococcus

Identifiers

PMID37773612
PMCPMC10541174
OpenAlexW4387168380

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.