Evidence map›Paper›PMID 37773556›Full record

ArticleJournal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing2025

Incidental parasympathetic cardiac denervation during atrial fibrillation ablation using high power short duration: a marker of long-term success.

Fabricio Vassallo, Lucas Corcino, Christiano Cunha, Eduardo Serpa, Carlos Lovatto, Aloyr Simoes, Hermes Carloni, Dalton Hespanhol, Dalbian Gasparini, Luiz Fernando Barbosa and 1 more

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In one paragraph

Article in Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Incidental ablation of ganglionated plexus during atrial fibrillation ablation.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2025
    Article
  2. Contemporary Trends in Pulsed Field Ablation for Cardiac Arrhythmias.Journal of cardiovascular development and disease · 2024
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Fabricio VassalloSchool of Medicine, Hospital Santa Casa Misericordia Vitoria, Dr. Joao Dos Santos Neves St, 143, Vila Rubim, Vitoria, Espirito Santo, 29025-023, Brazil. fsvassallo@cardiol.br.ORCID http://orcid.org/0000-0003-3915-4309
Lucas CorcinoSchool of Medicine, Hospital Santa Casa Misericordia Vitoria, Dr. Joao Dos Santos Neves St, 143, Vila Rubim, Vitoria, Espirito Santo, 29025-023, Brazil.
Christiano CunhaSchool of Medicine, Hospital Santa Casa Misericordia Vitoria, Dr. Joao Dos Santos Neves St, 143, Vila Rubim, Vitoria, Espirito Santo, 29025-023, Brazil.
Eduardo SerpaSchool of Medicine, Hospital Santa Casa Misericordia Vitoria, Dr. Joao Dos Santos Neves St, 143, Vila Rubim, Vitoria, Espirito Santo, 29025-023, Brazil.
Carlos LovattoSchool of Medicine, Hospital Santa Casa Misericordia Vitoria, Dr. Joao Dos Santos Neves St, 143, Vila Rubim, Vitoria, Espirito Santo, 29025-023, Brazil.
Aloyr SimoesSchool of Medicine, Hospital Santa Casa Misericordia Vitoria, Dr. Joao Dos Santos Neves St, 143, Vila Rubim, Vitoria, Espirito Santo, 29025-023, Brazil.
Hermes CarloniSchool of Medicine, Hospital Santa Casa Misericordia Vitoria, Dr. Joao Dos Santos Neves St, 143, Vila Rubim, Vitoria, Espirito Santo, 29025-023, Brazil.
Dalton HespanholSchool of Medicine, Hospital Santa Casa Misericordia Vitoria, Dr. Joao Dos Santos Neves St, 143, Vila Rubim, Vitoria, Espirito Santo, 29025-023, Brazil.
Dalbian GaspariniSchool of Medicine, Hospital Santa Casa Misericordia Vitoria, Dr. Joao Dos Santos Neves St, 143, Vila Rubim, Vitoria, Espirito Santo, 29025-023, Brazil.
Luiz Fernando BarbosaSchool of Medicine, Hospital Santa Casa Misericordia Vitoria, Dr. Joao Dos Santos Neves St, 143, Vila Rubim, Vitoria, Espirito Santo, 29025-023, Brazil.
Andre SchmidtInternal Medicine Department of Ribeirao Preto Medical School, University of Sao Paulo (USP), Ribeirao Preto, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere are multiple factors in both technique and substrate that lead to recurrence of atrial fibrillation after ablation. We sought to examine whether the degree of heart rate increase (HRI) caused by concurrent high-power-short-duration (HPSD) incidental parasympathetic denervation during AF ablation predicts long term success. Between December 2018 and December 2021, prospectively enrolled 214 patients who presented in sinus rhythm at AF ablation. Used 50 W of power and contact force (CF) of 5-15 g and 10-20 g at a flow rate of 40 mL/min on the anterior and posterior left atrial walls, respectively.

resultsMales were 143 (66.8%) and paroxysmal was 124 (57.9%) patients. Mean age 61.1 ± 12.3 years and follow-up time was 32.8 ± 13.2 months. Arrhythmia occurred after 90 days in 39 (18.2%) patients, 19 (48.7%) from the paroxysmal and 20 (51.3%) from the persistent AF patients. Recurrence group showed a lower HRI from a mean of 57 ± 7.7 to 64.4 ± 10.4 bpm (12.3%) while in success group HRI was from 53.8 ± 9.7 to 66.8 ± 11.6 bpm [(24.2%) p = 0.04]. We divided HRI in 3 percentiles of ≤ 8%, > 8 ≤ 37% and > 37%. A predictor of recurrence was identified in those in the first (< 8%, p = 0.006) and a predictor of success in the later (> 37%, p = 0.01) HRI percentile.

conclusionAtrial fibrillation ablation with HPSD incidental cardiac parasympathetic denervation identified that patients with lower heart rate increase are prone to recurrence while those with higher heart rate increase had higher maintenance of sinus rhythm at a long-term follow-up.

Indexed as

Atrial FibrillationCatheter AblationParasympathetic Nervous SystemAgedFemaleHeart RateHumansMaleMiddle AgedProspective StudiesRecurrenceTreatment OutcomeAtrial fibrillationAtrial tachyarrhythmiaAutonomic denervationCatheter ablationHigh-power short-duration and contact forceRecurrence rate

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.