Evidence map›Paper›PMID 37773457›Full record

ArticleActa neurochirurgica2023

The association between blood pressure at admission and in-hospital mortality in patients with subarachnoid hemorrhage.

Wei Zhou, Yi He

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Article in Acta neurochirurgica, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

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1 citing paper in PubMed.

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5 · Who and what money

Authors and funding

2 authors.

Wei ZhouDepartment of Neurosurgery, The Affiliated Changzhou Second People's Hospital of Nanjing Medical University, 68 Gehu Middle Road, Wujin District, Changzhou, 213161, Jiangsu, China.
Yi HeDepartment of Neurosurgery, The Affiliated Changzhou Second People's Hospital of Nanjing Medical University, 68 Gehu Middle Road, Wujin District, Changzhou, 213161, Jiangsu, China. yihe2nd@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe objective of this study was to examine the association between mean arterial pressure (MAP) at admission and in-hospital mortality among patients diagnosed with subarachnoid hemorrhage (SAH).

methodsIn this cohort study, 1420 SAH patients were categorized into four groups based on quartiles of MAP: <82 mmHg group, 82-93 mmHg group, 93-103 mmHg group, and >103 mmHg group. Furthermore, the X-tile program was used to divide all patients into four groups: < 81.7 mmHg group, 81.7-92.3 mmHg group, 92.3-103.7 mmHg group, and > 103.7 mmHg group. The association between MAP and in-hospital mortality of SAH patients was evaluated using univariate and multivariable Cox proportional hazards models. A restricted cubic spline (RCS) was plotted to explore the association between MAP at admission and in-hospital mortality in patients with SAH.

resultsThe median follow-up duration was 7.87 days, during which, 1219 (85.85%) patients survived. After adjusting for confounding factors, MAP <82 mmHg (hazard ratio (HR)=1.67, 95% confidence interval (CI): 1.08-2.57) or MAP >103 mmHg (HR=2.13, 95% CI: 1.38-3.29) was associated with increased risk of in-hospital mortality of SAH patients. Subgroup analysis depicted that MAP <82 mmHg or MAP >103 mmHg was associated with increased risk of in-hospital mortality in male patients or those aged ≥ 65 years. MAP >103 mmHg was linked with elevated risk of in-hospital mortality in patients aged <65 years; individuals with normal and underweight, overweight, and obesity; or people with hypertension.

conclusionThe findings may offer a preliminary estimate of the optimum range for SAH patients for future randomized trials.

Indexed as

Subarachnoid HemorrhageBlood PressureCohort StudiesHospitalizationHospital MortalityHumansMaleBlood pressureIn-hospital mortalityMean arterial pressureSubarachnoid hemorrhage

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.