Evidence map›Paper›PMID 37773324›Full record

ArticleScientific reports2023

Amide proton transfer imaging-arterial spin labeling mismatch: a new imaging biomarker for pilocytic astrocytoma.

Adhithyan Rajendran, Chidambaranathan Natesan, Prashanth Jawahar, Sushama Patil, Srinivas Chilukuri, Siddhartha Ghosh, Roopesh Kumar, Rakesh Jalali

Abstract read
In one paragraph

Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Adhithyan RajendranApollo Proton Cancer Centre, Chennai, India.
Chidambaranathan NatesanApollo Proton Cancer Centre, Chennai, India.
Prashanth JawaharApollo Proton Cancer Centre, Chennai, India.
Sushama PatilApollo Proton Cancer Centre, Chennai, India.
Srinivas ChilukuriApollo Proton Cancer Centre, Chennai, India.
Siddhartha GhoshApollo Proton Cancer Centre, Chennai, India.
Roopesh KumarApollo Proton Cancer Centre, Chennai, India.
Rakesh JalaliApollo Proton Cancer Centre, Chennai, India. rjalali@apollohospitals.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We describe the potential utility of Amide Proton Transfer weighted (APTw) Magnetic Resonance Imaging and arterial spin labeling (ASL) in characterizing pilocytic astrocytoma (PA), a type of brain tumor that can be challenging to accurately diagnose and treat. The study included 50 patients with solid or predominantly solid intra-cranial and intra-axial tumors, with 25 patients diagnosed with PA and 25 patients diagnosed with other types of tumors. The study found that the APTw imaging-arterial spin labeling (ASL) mismatch is a new imaging biomarker that could be used to differentiate PA from other types of tumors with a high degree of sensitivity and specificity. The results suggest that APTw imaging and ASL may be useful in characterizing PA, potentially improving diagnosis and treatment planning for this type of brain tumor.

Indexed as

AstrocytomaBrain NeoplasmsAmidesBiomarkersHumansMagnetic Resonance ImagingProtonsSpin LabelsAmidesBiomarkersProtonsSpin Labels

Identifiers

PMID37773324
PMCPMC10541908

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.