Evidence map›Paper›PMID 37773294›Full record

ArticleAnnals of hematology2023

Effectiveness of single-dose 6 mg pegfilgrastim in mobilizing peripheral blood stem cells in allogeneic hematopoietic cell transplantation donors.

Junjie Cao, Aizhen Li, Renzhi Pei, Ying Lu, Dong Chen, Xiaohong Du, Xuhui Liu, Shuangyue Li, Peipei Ye

Abstract read
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In one paragraph

Article in Annals of hematology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Junjie Cao *Department of Hematology, The Affiliated People's Hospital of Ningbo University, Ningbo, China. cjjxx01@126.com.
Aizhen Li *Department of Gastrointestinal Surgery, Ningbo University, Ningbo, China.ORCID http://orcid.org/0000-0001-5570-9007
Renzhi PeiDepartment of Hematology, The Affiliated People's Hospital of Ningbo University, Ningbo, China.
Ying LuDepartment of Hematology, The Affiliated People's Hospital of Ningbo University, Ningbo, China. rmluying@nbu.edu.cn.
Dong ChenDepartment of Hematology, The Affiliated People's Hospital of Ningbo University, Ningbo, China.
Xiaohong DuDepartment of Hematology, The Affiliated People's Hospital of Ningbo University, Ningbo, China.
Xuhui LiuDepartment of Hematology, The Affiliated People's Hospital of Ningbo University, Ningbo, China.
Shuangyue LiDepartment of Hematology, The Affiliated People's Hospital of Ningbo University, Ningbo, China.
Peipei YeDepartment of Hematology, The Affiliated People's Hospital of Ningbo University, Ningbo, China.
Ningbo University · CN

Funding

Ningbo Medical & Health Leading Academic Discipline Project 2022-S05Ningbo Public welfare project 2019C50071Ningbo Social and Development project 2016C51018Yinzhou District Social and Development project YZ2017-59Zhejiang Medical Health Science and Technology Project 2023KY1143
6 · The paper itself

Abstract

A single injection of 12 mg pegfilgrastim was used to mobilize peripheral blood progenitor cells (PBPCs) from healthy donors in some studies. The purpose of this study was to determine if 6 mg of pegfilgrastim was effective and safe for mobilizing CD34+ cells in donors for allogeneic hematopoietic stem cell transplantation. We conducted a retrospective case-matched design. A single dosage of 6 mg pegfilgrastim was used to mobilize PBPCs from 60 healthy donors. Granulocyte colony-stimulating factor (G-CSF, 10 μg/kg) was administered daily to the matched donors. Leukapheresis was scheduled to commence on day 4 of the mobilization regimen. The median yielded CD34+ cell in the pegfilgrastim group was higher than those in the G-CSF group, at 5.06 × 10

Indexed as

Hematopoietic Stem Cell TransplantationPeripheral Blood Stem CellsPeripheral Blood Stem Cell TransplantationAntigens, CD34Blood DonorsFilgrastimGranulocyte Colony-Stimulating FactorHematopoietic Stem Cell MobilizationHumansPolyethylene GlycolsRetrospective StudiesAntigens, CD34FilgrastimGranulocyte Colony-Stimulating FactorpegfilgrastimPolyethylene GlycolsAllogeneic donorsPegfilgrastimRecombinant human granulocyte colony-stimulating factorStem cell mobilization

Identifiers

PMID37773294
OpenAlexW4387178767

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.