ArticleScientific reports2023
Decreased diastolic hydraulic forces incrementally associate with survival beyond conventional measures of diastolic dysfunction.
Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Atrioventricular Area Difference Aids Diastolic Filling in Patients with Repaired Tetralogy of Fallot.Pediatric cardiology · 2025Article
- Left Ventricular Diastolic Function in Children with Atrial Septal Defects Improves After Closure by Means of Increased Hydraulic Force.Pediatric cardiology · 2025Article
- Exercise cardiovascular magnetic resonance shows improved diastolic filling by atrioventricular area difference in athletes and controls.Journal of applied physiology (Bethesda, Md. : 1985) · 2024Article
- Diastology of the Transplanted Heart: Is the Geometrical Relationship of the Left Atrium the Missing Link?Journal of the American Heart Association · 2024Article
- Diastolic Filling in Patients After Heart Transplantation Is Impaired Due to an Altered Geometrical Relationship Between the Left Atrium and Ventricle.Journal of the American Heart Association · 2024Article
- Hydraulic forces assist left ventricular filling in aortic stenosis at baseline and after valve replacement.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic ResonanceObservational
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Decreased hydraulic forces during diastole contribute to reduced left ventricular (LV) filling and heart failure with preserved ejection fraction. However, their association with diastolic function and patient outcomes are unknown. The aim of this retrospective, cross-sectional study was to determine the mechanistic association between diastolic hydraulic forces, estimated by echocardiography as the atrioventricular area difference (AVAD), and both diastolic function and survival. Patients (n = 5176, median [interquartile range] 5.5 [5.0-6.1] years follow-up, 1213 events) were selected from the National Echo Database Australia (NEDA) based on the presence of relevant transthoracic echocardiographic measures, LV ejection fraction (LVEF) ≥ 50%, heart rate 50-100 beats/minute, the absence of moderate or severe valvular disease, and no prior prosthetic valve surgery. NEDA contains echocardiographic and linked national death index mortality outcome data from 1985 to 2019. AVAD was calculated as the cross-sectional area difference between the LV and left atrium. LV diastolic dysfunction was graded according to 2016 guidelines. AVAD was weakly associated with E/e', left atrial volume index, and LVEF (multivariable global R
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