ArticleEuropean journal of medical research2023
Relationship between cortisol and diabetic microvascular complications: a retrospective study.
Article in European journal of medical research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 13 citations in OpenAlex.
- Associations of stress hormones, autonomic function, and endothelial function in patients with diabetes.Endocrine journal · 2026Article
- Pre-Diagnostic Plasma Endogenous Steroids and the Risk of Exfoliation Glaucoma.Investigative ophthalmology & visual science · 2026Article
- Pre-diagnostic plasma endogenous steroids and the risk of exfoliation glaucoma.medRxiv : the preprint server for health sciences · 2026Article
- Sympathetic Stress and Sleep Loss in Diabetic Retinopathy: Links to Retinal Blood-Flow Control.Biomedicines · 2026Review
- Insulin Resistance and Inflammation.International journal of molecular sciences · 2026Review
- Plasma miR-98-5p as a candidate biomarker of pain severity in oxaliplatin-induced peripheral neuropathy related to NGF and catecholamine dysregulation.Frontiers in molecular biosciences · 2026Article
- Adrenal cortex senescence: an ageing-related pathology?Journal of endocrinological investigation · 2025Review
- A Cross-Tissue Transcriptome-Wide Association Study Reveals Novel Susceptibility Genes for Diabetic Kidney Disease in the FinnGen Cohort.Biomedicines · 2025Article
- Behavioral, Physiological, and Pathological Approaches of Cortisol in Dogs.Animals : an open access journal from MDPI · 2024Review
- Endocrine Disorders in Nephrotic Syndrome-A Comprehensive Review.Biomedicines · 2024Review
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveWe aimed to investigate whether serum cortisol associate with diabetic microvascular compliments in patients with type 2 diabetes mellitus (T2DM). MATERIALS AND
methodsThe subjects were recruited from hospitalized patients with T2DM from 2019 to 2021. The odds ratios (OR) and corresponding 95% confidence intervals (CI) in relation to cortisol quartiles were obtained by multiple logistic regression analysis.
results(1) Cortisol level was positively correlated with the severity of microalbuminuria. The OR (95% CI) of microalbuminuria and macroalbuminuria in the last quartile were 3.396 (2.030, 5.682) and 8.407 (3.726, 18.971) compared with the first quartile (p < 0.001). (2) Cortisol level was positively correlated with the severity of diabetic retinopathy (DR). The OR (95% CI) of non-proliferative diabetic retinopathy group (NPDR) and proliferative diabetic retinopathy group (PDR) in the last quartile were 2.007 (1.401, 2.875) and 7.122 (2.525, 20.090) compared with the first quartile. (3) Elevated cortisol level was associated with diabetic peripheral neuropathy. The OR (95% CI) of diabetic peripheral neuropathy (DPN) in the last quartile was 1.956 (1.371, 2.792) and that in the third quartile was 1.854 (1.319, 2.608).
conclusionsHigh serum cortisol levels were significantly associated with diabetic microvascular compliments in inpatients. Its causality remains to be further studied. CLINICAL TRIAL REGISTRATION NUMBER: ChiCTR2100051749.
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