Evidence map›Paper›PMID 37772475›Full record

ArticleCancer medicine2023

Social inequality in cancer survivorship: Educational differences in health-related quality of life among 27,857 cancer survivors in Denmark.

Anne Katrine Graudal Levinsen, Trille Kristina Kjaer, Lau Caspar Thygesen, Thomas Maltesen, Erik Jakobsen, Ismail Gögenur, Michael Borre, Peer Christiansen, Robert Zachariae, Peter Christensen and 8 more

Open access · goldAbstract read
In one paragraph

Article in Cancer medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 19 citations in OpenAlex.

  1. Cancer and Health Inequalities.British journal of cancer · 2026
    Review
  2. Association of social determinants of health and physical functioning among breast cancer survivors.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  3. Article
  4. Article
  5. Social inequalities in cancer in Germany: a call to action.Journal of cancer research and clinical oncology · 2026
    Review
  6. Article
  7. Article
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  9. Article
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  13. Employment status among cancer survivors in a Late Effects Clinic in Denmark.Journal of cancer survivorship : research and practice · 2025
    Article
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  15. Article
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  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 10 institutions in 2 countries.

Anne Katrine Graudal LevinsenSurvivorship and Inequality in Cancer, Danish Cancer Institute, Copenhagen, Denmark.ORCID 0000-0003-0906-1873
Trille Kristina KjaerSurvivorship and Inequality in Cancer, Danish Cancer Institute, Copenhagen, Denmark.
Lau Caspar ThygesenNational Institute of Public Health, University of Southern Denmark, Copenhagen, Denmark.
Thomas MaltesenStatistics and Data Analysis, Danish Cancer Institute, Copenhagen, Denmark.
Erik JakobsenDepartment of Thoracic surgery, Odense University hospital, Odense, Denmark.
Ismail GögenurDept. Surgery, Center for Surgical Science, Zealand University Hospital, Køge, Denmark.
Michael BorreDepartment of Urology, Aarhus University Hospital, Aarhus, Denmark.
Peer ChristiansenDanish Breast Cancer Group Center and Clinic for Late Effects, Aarhus, Denmark.
Robert ZachariaeDanish Breast Cancer Group Center and Clinic for Late Effects, Aarhus, Denmark.
Peter ChristensenDanish Cancer Society Centre for Research on Survivorship and Late Adverse Effects After Cancer in the Pelvic Organs, Department of Surgery, Aarhus University Hospital, Aarhus, Denmark.
Søren LaurbergDanish Cancer Society Centre for Research on Survivorship and Late Adverse Effects After Cancer in the Pelvic Organs, Department of Surgery, Aarhus University Hospital, Aarhus, Denmark.
Peter de Nully BrownDepartment of Hematology, Rigshospitalet, Copenhagen, Denmark.
Lisbet Rosenkrantz HölmichDepartment of Plastic Surgery, Copenhagen University Hospital, Herlev, Denmark.
Christoffer JohansenCancer late effects, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
Susanne K KjaerUnit of Virus, Lifestyle and Genes, Danish Cancer Institute, Copenhagen, Denmark.ORCID 0000-0002-8347-1398
Lonneke van de Poll-FranseDepartment of Psychosocial Research and Epidemiology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
Lena SaltbaekSurvivorship and Inequality in Cancer, Danish Cancer Institute, Copenhagen, Denmark.
Susanne Oksbjerg DaltonSurvivorship and Inequality in Cancer, Danish Cancer Institute, Copenhagen, Denmark.ORCID 0000-0002-5485-2730
Aarhus University Hospital · DKDanish Cancer Society · DKZealand University Hospital · DKUniversity of Copenhagen · DKDanish Breast Cancer Cooperative Group · DKHerlev Hospital · DKOdense University Hospital · DKRigshospitalet · DKTilburg University · NLUniversity of Southern Denmark · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWith a growing population of cancer survivors in Denmark, the evaluation of health-related quality of life (HRQoL) has become increasingly important. We describe variations in HRQoL between educational groups in a national population of cancer survivors.

methodsWe conducted a cross-sectional questionnaire study among breast, prostate, lung, and colon cancer survivors diagnosed in 2010-2019 in Denmark. We used the EORTC QLQ-C30 to assess HRQoL including physical, role, emotional, cognitive, social functioning, and symptoms (fatigue, nausea and vomiting, pain, dyspnea, insomnia, appetite loss, constipation, diarrhea, and financial difficulties). Information on educational level and clinical data were extracted from national registers and clinical databases. Levels of impaired functioning and severe symptoms were identified using newly established thresholds for clinical importance. Multivariate logistic regression was used to examine associations between education and HRQoL. All statistical tests were 2-sided.

resultsIn total, 27,857 (42%) participated in the study. Up to 72% and 75% of cancer survivors with short education (≤9 years) reported impaired functioning and severe symptoms, respectively. Cancer survivors with short compared to long education (>12 years) were more likely to report impaired functioning and severe symptoms, with for example significantly higher odds ratios (ORs) for impaired physical function (breast OR = 2.41, 99% CI = 2.01-2.89; prostate OR = 1.81, 99% CI = 1.48-2.21; lung OR = 2.97, 99% CI = 1.95-4.57; and colon cancer OR = 1.69, 99% CI = 1.28-2.24).

conclusionsCancer survivors with short education are at greater risk of impaired HRQoL than survivors with long education 2-12 years after diagnosis. This underscores the need for systematic screening and symptom management in cancer aftercare, in order to reach all cancer survivors, also cancer survivors with short education.

Indexed as

Cancer SurvivorsColonic NeoplasmsCross-Sectional StudiesDenmarkHumansMaleQuality of LifeSocioeconomic FactorsSurveys and Questionnairescancer survivorshiphealth-related quality of lifesocial inequality

Identifiers

PMID37772475
PMCPMC10587985
OpenAlexW4387158077

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.