Evidence map›Paper›PMID 37772081›Full record

ReviewFrontiers in endocrinology2023

ACTH-producing small cell neuroendocrine carcinoma from the gallbladder: a case report and literature review.

Xiaofang Zhang, Dihua Huang, Xiaojie Pan, Qiya Si, Qiaoying You

Open access · goldAbstract readCase ReportsReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in endocrinology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Xiaofang ZhangDepartment of Endocrinology, Shaoxing People's Hospital, Shaoxing, Zhejiang, China.
Dihua HuangDepartment of Endocrinology, Shaoxing People's Hospital, Shaoxing, Zhejiang, China.
Xiaojie PanDepartment of Endocrinology, Shaoxing People's Hospital, Shaoxing, Zhejiang, China.
Qiya SiDepartment of Endocrinology, Shaoxing People's Hospital, Shaoxing, Zhejiang, China.
Qiaoying YouDepartment of Endocrinology, Shaoxing People's Hospital, Shaoxing, Zhejiang, China.
Shaoxing People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ectopic adrenocorticotropic hormone syndrome (EAS) is a condition of hypercortisolism caused by non-pituitary tumors that secrete adrenocorticotropic hormone (ACTH). A rare occurrence of this syndrome is due to an ACTH-producing neuroendocrine tumor that originates from the gallbladder. One patient with severe hypokalemia and alkalosis was admitted to our hospital. Clinical presentations and radiographic findings confirmed the diagnosis of an aggressive ACTH-producing gallbladder malignancy with multiple liver metastases. The diagnosis was verified by pathological and immunohistochemical measurements from a biopsy of the hepatic metastasis. A literature review identified only four similar cases had been reported. Despite being rare and having a poor prognosis, hormone-producing neuroendocrine tumors that derive from the gallbladder should be considered in the differential diagnosis of ectopic ACTH syndrome.

Indexed as

ACTH Syndrome, EctopicAdrenocorticotropic HormoneCarcinoma, NeuroendocrineCarcinoma, Small CellGallbladder NeoplasmsLiver NeoplasmsAgedHumansMaleAdrenocorticotropic Hormonecase reportCushing syndromeectopic adrenocorticotropic hormone syndromegallbladderneuroendocrine tumor

Identifiers

PMID37772081
PMCPMC10523022
OpenAlexW4386695735

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.