Evidence map›Paper›PMID 37772080›Full record

ArticleFrontiers in endocrinology2023

A clinically useful and biologically informative genomic classifier for papillary thyroid cancer.

Steven Craig, Cynthia Stretch, Farshad Farshidfar, Dropen Sheka, Nikolay Alabi, Ashar Siddiqui, Karen Kopciuk, Young Joo Park, Moosa Khalil, Faisal Khan and 2 more

2 registry-linked trialsAbstract read
In one paragraph

Article in Frontiers in endocrinology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06133374 recruitingnot on this mapstarted 2024, after this paper: background citation

Concordance of Molecular Classification Based on Fine Needle Biopsy (FNB) and Surgical Samples

TypeobservationalSponsorUniversity of CalgaryRan2024 to 2028Enrolled130ConditionsPapillary Thyroid Cancer
NCT07584447 not yet recruitingnot on this mapstarted 2026, after this paper: background citation

Clinical Utility of Preoperative Thyroid GuidePx® Testing

TypeobservationalSponsorUniversity of CalgaryRan2026 to 2029Enrolled85ConditionsPapillary Thyroid Cancer, Papillary Thyroid Carcinoma
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Guideline
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Steven CraigDepartment of Surgery, Illawarra Shoalhaven Local Health District, Wollongong, NSW, Australia.
Cynthia StretchDepartment of Oncology, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.
Farshad FarshidfarDepartment of Oncology, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.
Dropen ShekaDepartment of Biochemistry & Molecular Biology, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.
Nikolay AlabiDepartment of Biochemistry & Molecular Biology, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.
Ashar SiddiquiO'Brien Centre for the Bachelor of Health Sciences, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.
Karen KopciukDepartment of Oncology, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.
Young Joo ParkDepartment of Internal Medicine, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Republic of Korea.
Moosa KhalilDepartment of Pathology and Laboratory Medicine, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.
Faisal KhanDepartment of Pathology and Laboratory Medicine, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.
Adrian HarveyDepartment of Surgery, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.
Oliver F BatheDepartment of Oncology, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Clinical management of papillary thyroid cancer depends on estimations of prognosis. Standard care, which relies on prognostication based on clinicopathologic features, is inaccurate. We applied a machine learning algorithm (

Indexed as

Carcinoma, PapillaryThyroid NeoplasmsGenomicsHumansIodine RadioisotopesProto-Oncogene Proteins B-rafThyroid Cancer, PapillaryTumor MicroenvironmentIodine RadioisotopesProto-Oncogene Proteins B-rafbiomarkerBRAFEZH2machine learningpapillary thyroid cancerprognosisrisk stratification

Identifiers

PMID37772080
PMCPMC10523308

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.