Evidence map›Paper›PMID 37771983›Full record

ArticleFrontiers in medicine2023

Effectiveness and safety of an atropine/midazolam and target controlled infusion propofol-based moderate sedation protocol during percutaneous endoscopic transgastric jejunostomy procedures in Parkinson's disease: a real-life retrospective observational study.

Antonietta Gerarda Gravina, Raffaele Pellegrino, Rosa De Micco, Mirco Dellavalle, Anna Grasso, Giovanna Palladino, Sara Satolli, Massimo Ciaravola, Alessandro Federico, Alessandro Tessitore and 2 more

Abstract read
In one paragraph

Article in Frontiers in medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Antonietta Gerarda GravinaDepartment of Precision Medicine, Hepatogastroenterology and Digestive Endoscopy Unit, University of Campania "Luigi Vanvitelli", Naples, Italy.
Raffaele PellegrinoDepartment of Precision Medicine, Hepatogastroenterology and Digestive Endoscopy Unit, University of Campania "Luigi Vanvitelli", Naples, Italy.
Rosa De MiccoDepartment of Advanced Medical and Surgical Sciences, Neurology Unit, University of Campania "Luigi Vanvitelli", Naples, Italy.
Mirco DellavalleDepartment of Woman, Child, General and Specialized Surgery, Anaesthesia and Intensive Care Unit, University of Campania "Luigi Vanvitelli", Naples, Italy.
Anna GrassoDepartment of Woman, Child, General and Specialized Surgery, Anaesthesia and Intensive Care Unit, University of Campania "Luigi Vanvitelli", Naples, Italy.
Giovanna PalladinoDepartment of Precision Medicine, Hepatogastroenterology and Digestive Endoscopy Unit, University of Campania "Luigi Vanvitelli", Naples, Italy.
Sara SatolliDepartment of Advanced Medical and Surgical Sciences, Neurology Unit, University of Campania "Luigi Vanvitelli", Naples, Italy.
Massimo CiaravolaDepartment of Woman, Child, General and Specialized Surgery, Anaesthesia and Intensive Care Unit, University of Campania "Luigi Vanvitelli", Naples, Italy.
Alessandro FedericoDepartment of Precision Medicine, Hepatogastroenterology and Digestive Endoscopy Unit, University of Campania "Luigi Vanvitelli", Naples, Italy.
Alessandro TessitoreDepartment of Advanced Medical and Surgical Sciences, Neurology Unit, University of Campania "Luigi Vanvitelli", Naples, Italy.
Marco RomanoDepartment of Precision Medicine, Hepatogastroenterology and Digestive Endoscopy Unit, University of Campania "Luigi Vanvitelli", Naples, Italy.
Fausto FerraroDepartment of Woman, Child, General and Specialized Surgery, Anaesthesia and Intensive Care Unit, University of Campania "Luigi Vanvitelli", Naples, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Patients with Parkinson's disease (PD), often elderly with various comorbidities, may require a continuous intestinal infusion of carbidopa/levodopa gel by the placement of a percutaneous endoscopic gastrostomy (PEG) with a jejunal tube (PEG-J) to improve their motor outcome and quality of life. However, it is unclear what is the best procedural sedation protocol for PEG-J procedures. Fifty patients with PD and indication for PEG-J procedure (implantation, replacement, removal) underwent, from 2017 to 2022, a sedation protocol characterized by premedication with atropine (0.01 mg/Kg

Indexed as

endoscopygastrostomyjejunal tubeParkinson’s diseasePEG-Jpercutaneous endoscopic gastrostomysedation

Identifiers

PMID37771983
PMCPMC10523572

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.