Evidence map›Paper›PMID 37771778›Full record

ArticleTheranostics2023

Discovery of a novel NAMPT inhibitor that selectively targets NAPRT-deficient EMT-subtype cancer cells and alleviates chemotherapy-induced peripheral neuropathy.

Minjee Kim, Hyeyoung Kim, Bu-Gyeong Kang, Jooyoung Lee, Taegun Kim, Hwanho Lee, Jane Jung, Myung Joon Oh, Seungyoon Seo, Myung-Jeom Ryu and 7 more

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. The role of NADnpj metabolic health and disease · 2025
    Review
  5. Review
  6. The role of nicotinamide adenine dinucleotide salvage enzymes in cardioprotection.Kardiochirurgia i torakochirurgia polska = Polish journal of cardio-thoracic surgery · 2024
    Review
  7. Review
  8. Inhibitors of NADInternational journal of molecular sciences · 2024
    Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 4 institutions in 3 countries.

Minjee KimGraduate School of Medical Science, Brain Korea 21 Project, Yonsei University College of Medicine, Seoul, 03722, Republic of Korea.
Hyeyoung KimGraduate School of Medical Science, Brain Korea 21 Project, Yonsei University College of Medicine, Seoul, 03722, Republic of Korea.
Bu-Gyeong KangDepartment of Chemistry and Nanoscience, Ewha Womans University, Seoul, 03760, Republic of Korea.
Jooyoung LeeDepartment of Biomedical Sciences, Yonsei University College of Medicine, Seoul, 03722, Republic of Korea.
Taegun KimDepartment of Biotechnology, College of Life Science and Biotechnology, Yonsei University, Seoul 03722, Republic of Korea.
Hwanho LeeGraduate School of Medical Science, Brain Korea 21 Project, Yonsei University College of Medicine, Seoul, 03722, Republic of Korea.
Jane JungGraduate School of Medical Science, Brain Korea 21 Project, Yonsei University College of Medicine, Seoul, 03722, Republic of Korea.
Myung Joon OhGraduate School of Medical Science, Brain Korea 21 Project, Yonsei University College of Medicine, Seoul, 03722, Republic of Korea.
Seungyoon SeoPrometabio Research Institute, Prometabio Co., Ltd. Hanam-si, Gyeonggi-do 12939, Republic of Korea.
Myung-Jeom RyuDepartment of Biomedical Sciences, Yonsei University College of Medicine, Seoul, 03722, Republic of Korea.
Yeojin SungGraduate School of Medical Science, Brain Korea 21 Project, Yonsei University College of Medicine, Seoul, 03722, Republic of Korea.
Yunji LeeGraduate School of Medical Science, Brain Korea 21 Project, Yonsei University College of Medicine, Seoul, 03722, Republic of Korea.
Jeonghun YeomPrometabio Research Institute, Prometabio Co., Ltd. Hanam-si, Gyeonggi-do 12939, Republic of Korea.
Gyoonhee HanDepartment of Biotechnology, College of Life Science and Biotechnology, Yonsei University, Seoul 03722, Republic of Korea.
Sun-Shin ChaDepartment of Chemistry and Nanoscience, Ewha Womans University, Seoul, 03760, Republic of Korea.
Hosung JungGraduate School of Medical Science, Brain Korea 21 Project, Yonsei University College of Medicine, Seoul, 03722, Republic of Korea.
Hyun Seok KimGraduate School of Medical Science, Brain Korea 21 Project, Yonsei University College of Medicine, Seoul, 03722, Republic of Korea.
Yonsei University · KREwha Womans University · KRPromundo · USCheck Point (Israel) · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Antineoplastic AgentsCytokinesEnzyme InhibitorsNicotinamide PhosphoribosyltransferasePentosyltransferasesPeripheral Nervous System DiseasesAnimalsCell Line, TumorEpithelial-Mesenchymal TransitionFemaleHumansLung NeoplasmsMiceXenograft Model Antitumor AssaysAntineoplastic AgentsCytokinesEnzyme InhibitorsNicotinamide Phosphoribosyltransferasenicotinamide phosphoribosyltransferase, humanPentosyltransferasesChemotherapy-induced peripheral neuropathy (CIPN)Epithelial-to-mesenchymal transition (EMT)NAMPT inhibitorSynthetic lethalityWallerian degeneration

Identifiers

PMID37771778
PMCPMC10526665
OpenAlexW4387110329

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.