Evidence map›Paper›PMID 37771765›Full record

ArticleTheranostics2023

Metabolite Neu5Ac triggers SLC3A2 degradation promoting vascular endothelial ferroptosis and aggravates atherosclerosis progression in ApoE

Peng Xiang, Qingqiu Chen, Le Chen, Jin Lei, Zhiyi Yuan, Hui Hu, Yining Lu, Xianmin Wang, Tingting Wang, Ruihong Yu and 4 more

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed
16.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

54 citing papers in PubMed, 63 citations in OpenAlex.

  1. Review
  2. Article
  3. Disulfidptosis: molecular mechanisms and therapeutic targets.Signal transduction and targeted therapy · 2026
    Review
  4. Review
  5. Review
  6. Review
  7. ETS‑1/ETS‑2 transcription factors in CVD (Review).International journal of molecular medicine · 2026
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. NPC1L1, stabilized by PABPC1/IGF2BP1, accelerates atherosclerosis by enhancing CYP11A1-mediated mitophagy and ferroptosis.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2026
    Article
  15. Article
  16. Article
  17. Article
  18. FBXO6 mediated ubiquitination of SLC3A2 drives ferroptosis in ulcerative colitis: a machine learning and SHAP discovery.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2026
    Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 1 country.

Peng XiangCollege of Pharmacy, Chongqing Medical University, 400010, Chongqing, China.
Qingqiu ChenCollege of Pharmacy, Chongqing Medical University, 400010, Chongqing, China.
Le ChenCollege of Pharmacy, Chongqing Medical University, 400010, Chongqing, China.
Jin LeiXi'an No.1 Hospital, The First Affiliated Hospital of Northwest University, Xi'an, 710002, Shaanxi, China.
Zhiyi YuanCollege of Pharmacy, Chongqing Medical University, 400010, Chongqing, China.
Hui HuCollege of Pharmacy, Chongqing Medical University, 400010, Chongqing, China.
Yining LuCollege of Pharmacy, Chongqing Medical University, 400010, Chongqing, China.
Xianmin WangCollege of Pharmacy, Chongqing Medical University, 400010, Chongqing, China.
Tingting WangCollege of Pharmacy, Chongqing Medical University, 400010, Chongqing, China.
Ruihong YuCollege of Pharmacy, Chongqing Medical University, 400010, Chongqing, China.
Wanping ZhangCollege of Pharmacy, Chongqing Medical University, 400010, Chongqing, China.
Jun ZhangCollege of Pharmacy, Chongqing Medical University, 400010, Chongqing, China.
Chao YuCollege of Pharmacy, Chongqing Medical University, 400010, Chongqing, China.
Limei MaCollege of Pharmacy, Chongqing Medical University, 400010, Chongqing, China.
Chongqing Medical and Pharmaceutical College · CNNorthwest University · CNChongqing Medical University · CNChina XD Group (China) · CNFirst Hospital of Xi'an · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AtherosclerosisFerroptosisFusion Regulatory Protein 1, Heavy ChainPlaque, AtheroscleroticAnimalsEndothelial CellsMiceMice, Knockout, ApoEFusion Regulatory Protein 1, Heavy ChainSlc3A2 protein, mouseatherosclerosis, endothelial inflammatory injuryNeu5Ac, ferroptosis, SLC3A2

Identifiers

PMID37771765
PMCPMC10526676
OpenAlexW4387110276

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.