Evidence map›Paper›PMID 37771737›Full record

ArticleAntimicrobial stewardship & healthcare epidemiology : ASHE2023

Synergy between infection control and antimicrobial stewardship programs to control carbapenem-resistant Enterobacterales.

Wanda Cornistein, Daniela Santonato, Paula Andrea Novau, Leonardo Guillermo Fabbro, Melisa Fernanda Jorge, Maria Agustina Malvicini, Viviana Vilches, Fernando Martin Iudica

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Antimicrobial stewardship & healthcare epidemiology : ASHE, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07167173 (Predictive Model for Multidrug Resistance in Patients Admitted to the Emergency Department With Sepsis), which is not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.0field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07167173 not yet recruitingnot on this mapstarted 2025, after this paper: background citation

Predictive Model for Multidrug Resistance in Patients Admitted to the Emergency Department With Sepsis

TypeobservationalSponsorHospital Italiano de Buenos AiresRan2025 to 2025Enrolled10,000ConditionsSepsis, Septic Shock
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Update on infection prevention in the ICU.Current opinion in critical care · 2025
    Review
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Wanda CornisteinInfection Prevention and Control Department, Hospital Universitario Austral, Buenos Aires, Argentina.ORCID https://orcid.org/0000-0003-2830-8552
Daniela SantonatoInfection Prevention and Control Department, Hospital Universitario Austral, Buenos Aires, Argentina.ORCID https://orcid.org/0000-0003-0020-9296
Paula Andrea NovauInfection Prevention and Control Department, Hospital Universitario Austral, Buenos Aires, Argentina.
Leonardo Guillermo FabbroInfection Prevention and Control Department, Hospital Universitario Austral, Buenos Aires, Argentina.
Melisa Fernanda JorgeInfection Prevention and Control Department, Hospital Universitario Austral, Buenos Aires, Argentina.
Maria Agustina MalviciniDepartment of Phamacy, Hospital Universitario Austral, Buenos Aires, Argentina.
Viviana VilchesMicrobiology Laboratory, Hospital Universitario Austral, Buenos Aires, Argentina.
Fernando Martin IudicaMedical Director, Hospital Universitario Austral, Buenos Aires, Argentina.
Hospital Universitario Austral · AR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Argentina is the third country in the world with the higher levels of CRE. The primary objective is to achieve an optimal result in the CRE infection rate after the implementation of an IPC program and antimicrobial stewardship programs (ASP) in a large teaching hospital in Argentina. Methods: Retrospective, observational study from January 2018 to December 2021, in a 220-bed tertiary care teaching hospital in Buenos Aires province. Actions aimed at CRE control and prevention included CRE and healthcare-associated infection (HAI) surveillance; compliance with hand hygiene, hospital hygiene, contact isolation precautions, and care bundles for the prevention of device-associated infections; optimization of antimicrobial treatments, antimicrobial consumption, education, and feedback. Results: Synergy between an ICP and ASP achieved controlled rate of CRE infections reaching the lowest levels during 2020 (0.08 episodes/1000 patient days). Colonization rate remained stable throughout the study period. Ventilator-associated pneumonia (VAP) rate showed a trend toward lower rates. Compliance with care bundles showed rates >85%. Antimicrobial consumption increased slightly during the study period (15%). Among high-impact antimicrobials, only colistin consumption increased. Conclusion: Our study demonstrates the sustained and beneficial impact of an IPC Program and an ASP to control CRE infection.

Identifiers

PMID37771737
PMCPMC10523542
OpenAlexW4387029303

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.