Evidence map›Paper›PMID 37771472›Full record

ArticleNon-coding RNA research2023

Firalink: A bioinformatics pipeline for long non-coding RNA data analysis.

Louis Chauviere, Lucien Hoffbeck, Muhammad Shoaib, Florent Tessier, Huseyin Firat, Venkata Satagopam, Yvan Devaux, COVIRNA consortium

Abstract read
In one paragraph

Article in Non-coding RNA research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Louis ChauviereFrom Firalis SA, Huningue, France.
Lucien HoffbeckFrom Firalis SA, Huningue, France.
Muhammad ShoaibLuxembourg Centre for Systems Biomedicine, Bioinformatics Core, University of Luxembourg, Belvaux, Luxembourg.
Florent TessierFrom Firalis SA, Huningue, France.
Huseyin FiratFrom Firalis SA, Huningue, France.
Venkata SatagopamLuxembourg Centre for Systems Biomedicine, Bioinformatics Core, University of Luxembourg, Belvaux, Luxembourg.
Yvan DevauxCardiovascular Research Unit, Department of Precision Health, Luxembourg Institute of Health, Strassen, Luxembourg.
COVIRNA consortium

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Summary: The Firalink bioinformatics pipeline has been developed to analyse long non-coding RNA (lncRNA) data generated by targeted sequencing. This pipeline has been first implemented for use with the FIMICS panel containing 2906 lncRNAs useful for investigations in cardiovascular disease. It has been subsequently tested and validated using a panel of lncRNAs targeting brain disease. The pipeline can be adapted to other targeted sequencing panels or other transcriptomics data (e.g. whole transcriptome) through a change of the reference genome/panel. Therefore, Firalink can be applied to different lncRNA panels and transcriptomics data targeting multiple diseases. Availability and implementation: The Firalink pipeline works on Linux and is freely available to non-commercial users at https://gitlab.lcsb.uni.lu/covirna/covirna-ext/covirna-firalink-pipeline. Access will be granted after contacting bioinformatics@firalis.com. The pipeline is implemented with the Nextflow workflow manager using Python and R scripts. It will remain available for at least two years following publication and will be regularly updated and upgraded. Supplementary information: For an example of the application of the Firalink pipeline using the FIMICS panel, see www.covirna.eu.

Identifiers

PMID37771472
PMCPMC10523182

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.