Evidence map›Paper›PMID 37771311›Full record

Observational studyESC heart failure2023

Prognostic value of the NEWS + Lactate score in patients with decompensated heart failure in the emergency department.

Mustafa Can Guzelce, Nese Colak, Gucluhan Ucar, Ertug Orhan

Abstract readObservational Study
In one paragraph

Observational study in ESC heart failure, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Mustafa Can GuzelceDepartment of Emergency Medicine, Faculty of Medicine, Dokuz Eylul University, Balcova, 35340, Izmir, Turkey.ORCID 0000-0003-4141-2661
Nese ColakDepartment of Emergency Medicine, Faculty of Medicine, Dokuz Eylul University, Balcova, 35340, Izmir, Turkey.
Gucluhan UcarDepartment of Emergency Medicine, Faculty of Medicine, Dokuz Eylul University, Balcova, 35340, Izmir, Turkey.
Ertug OrhanDepartment of Emergency Medicine, Faculty of Medicine, Dokuz Eylul University, Balcova, 35340, Izmir, Turkey.ORCID 0000-0001-8982-0096

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsThe National Early Warning Score (NEWS) is a scoring system that predicts increased mortality and morbidity in critical diseases. The National Early Warning Score + Lactate (NEWS + L) score was created by adding lactate values to this scoring system. In our study, we aimed to determine the value of the NEWS + L score in predicting clinical deterioration in patients presenting with acute decompensated heart failure (chronic heart failure). METHODS AND

resultsIn this observational, cross-sectional study, patients with decompensated heart failure who were admitted to the emergency department between 1 October 2020 and 31 December 2020 were included. Patients were divided into two groups: those with and without poor prognostic outcomes. The main outcomes were in-hospital mortality, discharge after treatment in the emergency department, admission to the ward, and admission to the intensive care unit. We analysed a total of 141 applications from 130 patients. The mean age was 72.6 ± 11.8 years, and 50.8% were female. Poor prognostic outcomes were observed in 92 (65%) patients. There was no difference between the patients with and without poor prognostic outcomes in terms of mean age, gender, and comorbidities, except for atrial fibrillation. There was a statistically significant difference between the patients without and with poor prognosis outcomes in terms of NEWS {3 [interquartile range (IQR): 0-5] and 6 [IQR: 3-8]} and NEWS + L scores [4.7 (IQR: 2.3-7.2) and 8.0 (IQR: 5.2-10.4)] (P < 0.001). The area under the curve values for predicting poor prognosis were calculated as 0.719 for NEWS, 0.734 for NEWS + L, and 0.601 for lactate values. The rate of poor prognostic outcomes was higher (79%) in patients with moderate and high NEWS scores. Patients with Q1 NEWS + L scores had a lower rate of poor prognostic outcomes, while patients with Q2, Q3, and Q4 scores of NEWS + L had a higher rate of poor prognostic outcomes.

conclusionsThe NEWS score and the addition of the lactate value to this score, the NEWS + L score, were higher in patients with poor prognostic outcomes who presented with decompensated heart failure in our emergency department. NEWS + L slightly outperformed the NEWS score in predicting prognosis. The NEWS + L score shows promise as a prognostic indicator for patients with decompensated heart failure presenting to the emergency department.

Indexed as

Early Warning ScoreHeart FailureAgedAged, 80 and overCross-Sectional StudiesEmergency Service, HospitalFemaleHumansLactic AcidMaleMiddle AgedPrognosisRetrospective StudiesROC CurveLactic AcidDecompensated heart failureEmergency departmentLactateNational Early Warning Score + Lactate scoreNEWSNEWS + L score

Identifiers

PMID37771311
PMCPMC10682865

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.