Evidence map›Paper›PMID 37771197›Full record

ArticleSmall (Weinheim an der Bergstrasse, Germany)2024

Enhancing ROS-Inducing Nanozyme through Intraparticle Electron Transport.

Zhongchao Yi, Xiaoyue Yang, Ying Liang, Fanny Chapelin, Sheng Tong

Open access · greenAbstract read
In one paragraph

Article in Small (Weinheim an der Bergstrasse, Germany), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Review
  6. Article
  7. Intraparticle Electron Transfer for Long-Lasting Tumor Chemodynamic Therapy.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Article
  8. Article
  9. Targeting ferroptosis opens new avenues in gliomas.International journal of biological sciences · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Zhongchao YiF. Joseph Halcomb III, M.D. Department of Biomedical Engineering, University of Kentucky, Lexington, KY, 40536, USA.
Xiaoyue YangF. Joseph Halcomb III, M.D. Department of Biomedical Engineering, University of Kentucky, Lexington, KY, 40536, USA.ORCID 0000-0002-5083-7883
Ying LiangNew York Blood Center, New York, NY, 10065, USA.
Fanny ChapelinShu Chien - Gene Lay Department of Bioengineering & Department of Radiology, University of California San Diego, La Jolla, CA, 92093, USA.
Sheng TongF. Joseph Halcomb III, M.D. Department of Biomedical Engineering, University of Kentucky, Lexington, KY, 40536, USA.ORCID 0000-0001-8632-7933
University of Kentucky · USNew York Blood Center · USUniversity of California San Diego · US

Funding

University of Kentucky Center for Cancer MetabolismP20GM121327 · NIGMS · UNIVERSITY OF KENTUCKY · PI Jianhang Jia · 2017 to 2026
$25.0M
Controllable In Vivo Genome Editing for Immune-Checkpoint Blockade in Solid TumorsR01EB026893 · NIBIB · UNIVERSITY OF KENTUCKY · PI TONG, SHENG · 2018 to 2022
$2.0M
NIBIB NIH HHS R01 EB026893NIBIB NIH HHS R01EB026893NIGMS NIH HHS P20 GM121327
6 · The paper itself

Abstract

Iron oxide nanoparticles (IONPs) have garnered significant attention as a promising platform for reactive oxygen species (ROS)-dependent disease treatment, owing to their remarkable biocompatibility and Fenton catalytic activity. However, the low catalytic activity of IONPs is a major hurdle in their clinical translation. To overcome this challenge, IONPs of different compositions are examined for their Fenton reaction under pharmacologically relevant conditions. The results show that wüstite (FeO) nanoparticles exhibit higher catalytic activity than magnetite (Fe

Indexed as

Ferrosoferric OxideNanoparticlesAnimalsElectron TransportFerric CompoundsFerrous CompoundsMiceReactive Oxygen SpeciesFerric CompoundsFerrosoferric OxideFerrous Compoundsferrous oxideReactive Oxygen SpeciesFenton reactioniron oxide nanoparticlesreactive oxygen specieswüstite nanoparticles

Identifiers

PMID37771197
PMCPMC10922328
OpenAlexW4387158016

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.