Evidence map›Paper›PMID 37771189›Full record

ArticleSmall (Weinheim an der Bergstrasse, Germany)2024

4D-Printable Photocrosslinkable Polyurethane-Based Inks for Tissue Scaffold and Actuator Applications.

Hossein Goodarzi Hosseinabadi, Arpan Biswas, Anant Bhusal, Ali Yousefinejad, Aastha Lall, Wolfram-Hubertus Zimmermann, Amir K Miri, Leonid Ionov

Abstract read
In one paragraph

Article in Small (Weinheim an der Bergstrasse, Germany), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Grayscale 4D Printing of Ferromagnetic Soft Materials.Small (Weinheim an der Bergstrasse, Germany) · 2025
    Article
  4. Review
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Hossein Goodarzi HosseinabadiFaculty of Engineering Sciences, Department of Biofabrication, University of Bayreuth, Ludwig Thoma Str. 36A, 95447, Bayreuth, Germany.ORCID 0000-0001-6841-2544
Arpan BiswasFaculty of Engineering Sciences, Department of Biofabrication, University of Bayreuth, Ludwig Thoma Str. 36A, 95447, Bayreuth, Germany.ORCID 0000-0002-7028-6388
Anant BhusalDepartment of Mechanical Engineering, Rowan University, 201 Mullica Hill Rd., Glassboro, NJ, 08028, USA.
Ali YousefinejadFaculty of Engineering Sciences, Department of Biofabrication, University of Bayreuth, Ludwig Thoma Str. 36A, 95447, Bayreuth, Germany.
Aastha LallFaculty of Engineering Sciences, Department of Biofabrication, University of Bayreuth, Ludwig Thoma Str. 36A, 95447, Bayreuth, Germany.
Wolfram-Hubertus ZimmermannInstitute of Pharmacology and Toxicology, University Medical Center Göttingen, Robert-Koch-Str. 40, 37075, Göttingen, Germany.
Amir K MiriDepartment of Mechanical Engineering, Rowan University, 201 Mullica Hill Rd., Glassboro, NJ, 08028, USA.
Leonid IonovFaculty of Engineering Sciences, Department of Biofabrication, University of Bayreuth, Ludwig Thoma Str. 36A, 95447, Bayreuth, Germany.ORCID 0000-0002-0770-6140

Funding

Bioprintable composite materials and microfluidic tools for vocal fold restoration and repairR01DC018577 · NIDCD · MCGILL UNIVERSITY · PI MONGEAU, LUC · 2021 to 2025
$2.5M
NIDCD NIH HHS R01 DC018577
6 · The paper itself

Abstract

4D printing recently emerges as an exciting evolution of conventional 3D printing, where a printed construct can quickly transform in response to a specific stimulus to switch between a temporary variable state and an original state. In this work, a photocrosslinkable polyethylene-glycol polyurethane ink is synthesized for light-assisted 4D printing of smart materials. The molecular weight distribution of the ink monomers is tunable by adjusting the copolymerization reaction time. Digital light processing (DLP) technique is used to program a differential swelling response in the printed constructs after humidity variation. Bioactive microparticles are embedded into the ink and the improvement of biocompatibility of the printed constructs is demonstrated for tissue engineering applications. Cell studies reveal above 90% viability in 1 week and ≈50% biodegradability after 4 weeks. Self-folding capillary scaffolds, dynamic grippers, and film actuators are made and activated in a humid environment. The approach offers a versatile platform for the fabrication of complex constructs. The ink can be used in tissue engineering and actuator applications, making the ink a promising avenue for future research.

Indexed as

InkTissue ScaffoldsHydrogelsPolyurethanesPrinting, Three-DimensionalTissue EngineeringHydrogelsPolyurethanes4D printingbi-modal molecular weight distributionbiocompatible polyurethane inkhydrogel digital light processing (DLP) printing

Identifiers

PMID37771189
PMCPMC10922657

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.