SynthesisArthritis research & therapy2023
Association of knee and hip osteoarthritis with the risk of falls and fractures: a systematic review and meta-analysis.
Synthesis in Arthritis research & therapy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed, 34 citations in OpenAlex.
- Feasibility and Preliminary Effectiveness of a Mobile App-Based Personalized Exercise Program in Older Patients With Chronic Knee Osteoarthritis: Pilot Randomized Controlled Trial.JMIR mHealth and uHealth · 2025Trial
- Mechanistic Pathways Linking Type 2 Diabetes Mellitus, Hypertension, and Osteoarthritis to Falls in Older Adults: A Scoping Review.Healthcare (Basel, Switzerland) · 2026Review
- Different durations of arthritis and hip fracture risk among middle-aged and older adults evidence from CHARLS 2011-2020.Clinical rheumatology · 2026Article
- Symptomatic knee osteoarthritis in older Thai adults: prevalence, risk factors, and associations with osteoporosis, sarcopenia, and fall risk-a nationwide cross-sectional study.BMC public health · 2026Article
- The interplay of risk factors for future falls and fall-related injuries among community-dwelling older adults: a Bayesian network analysis.BMC public health · 2026Article
- Altered Spatiotemporal and Kinematic Gait in Patients with Knee Osteoarthritis.Journal of functional morphology and kinesiology · 2026Article
- Knee Osteoarthritis (KOA) Severity Influences Proximal Femoral Biomechanics and Predicts Pertrochanteric Fracture Instability: A Retrospective Radiographic Study.Medicina (Kaunas, Lithuania) · 2026Observational
- Social Determinants of Health and Access to Orthopedic Care Among Seniors in Little Havana.Cureus · 2026Article
- Evaluating Gait Quality in People with Hip Osteoarthritis During Habitual and Fast Walking Using a Trunk Inertial Measurement Unit in Clinical Settings.Sensors (Basel, Switzerland) · 2026Article
- Multivariate analysis of newly diagnosed hip, knee, and combined hip and knee Osteoarthritis and recurrent fall risk: data from the Osteoarthritis Initiative.Frontiers in medicine · 2026Article
- Genetically Predicted Intervertebral Disc Degeneration and Risk of Osteoarthritis: A Two-Sample Mendelian Randomization Study with Mediation Analysis of Obesity and Sarcopenia.Journal of pain research · 2026Article
- Preoperative treatment and postoperative outcomes in osteoporotic patients with vertebral fractures: a longitudinal database study.Journal of bone and mineral metabolism · 2025Article
- Preoperative Clinical Phenotyping for Individualised Rehabilitation in End-Stage Knee Osteoarthritis.Journal of functional morphology and kinesiology · 2025Article
- Exploring the role of intrinsic and extrinsic factors on the associations between sarcopenia and falls in older adults.Scientific reports · 2025Article
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- The Impact of Total Hip Arthroplasty on the Incidence of Hip Fractures in Romania.Journal of clinical medicine · 2025Article
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- Association between ethylene oxide exposure and osteoarthritis risk: an analysis of NHANES data (2013-2014 and 2017-2018).Frontiers in public health · 2025Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveStudies evaluating the association of knee and hip osteoarthritis (OA) with falls and fractures have inconsistent findings. We aimed to investigate associations of symptomatic and radiographic knee and hip OA with risk of falls, recurrent falls, and fractures.
methodsWe conducted an electronic search of databases from inception to February 2023. Two authors independently screened studies, extracted data, and assessed the risk of bias using the Newcastle-Ottawa Scale tool in eligible studies. Pooled odds ratios (ORs) with 95% confidence intervals (CIs) were calculated using random-effects models.
resultsOf 17 studies included (n = 862849), 2 had a high risk of bias. Among studies that evaluated falls or fractures as outcomes, 7/8 (87.5%) and 5/11 (45.5%) were self-reported, respectively. Both symptomatic knee and hip OA were associated with increased risk of recurrent falls (knee: OR = 1.55, 95% CI 1.10 to 2.18; hip: OR = 1.50, 95% CI 1.28 to 1.75) but not falls or fractures. Radiographic knee OA increased risk of falls (OR = 1.28, 95% CI 1.03 to 1.59) and did not significantly increase risk of recurrent falls (OR = 1.39, 95% CI 0.97 to 1.97) or fractures (OR = 1.22, 95% CI 0.99 to 1.52). Radiographic hip OA decreased the risk of recurrent falls (OR = 0.70, 95% CI 0.51 to 0.96) but had no statistically significant association with fractures (OR = 1.16, 95% CI 0.79 to 1.71).
conclusionSymptomatic knee and hip OA were both associated with an increased risk of recurrent falls, and radiographic knee OA was associated with an increased risk of falls. No statistically significant associations of radiographic and symptomatic knee or hip OA with fractures were found.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.