Evidence map›Paper›PMID 37770783›Full record

ArticleBulletin of experimental biology and medicine2023

Changes in Microcirculation in the Brain, Heart, and Liver in Female Rats with Translational Model of Alcoholic Cardiomyopathy.

I B Tsorin, A O Efimova, M V Vititnova, E O Ionova, V V Barchukov, S A Simonenko, S A Kryzhanovskii

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Article in Bulletin of experimental biology and medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 69% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

I B TsorinV. V. Zakusov Research Institute of Pharmacology, Moscow, Russia. tsorinib@yandex.ru.
A O EfimovaV. V. Zakusov Research Institute of Pharmacology, Moscow, Russia.
M V VititnovaV. V. Zakusov Research Institute of Pharmacology, Moscow, Russia.
E O IonovaV. V. Zakusov Research Institute of Pharmacology, Moscow, Russia.
V V BarchukovV. V. Zakusov Research Institute of Pharmacology, Moscow, Russia.
S A SimonenkoV. V. Zakusov Research Institute of Pharmacology, Moscow, Russia.
S A KryzhanovskiiV. V. Zakusov Research Institute of Pharmacology, Moscow, Russia.
Institute of Pharmacology Russian Academy of Medical Sciences · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We studied some features of blood and lymph microcirculation in the brain, heart, and liver of female rats with developed alcoholic cardiomyopathy. In female rats after 24-week forced consumption of 10% ethanol solution, the size and inotropic function of the heart were measured by echocardiography. Microcirculation in the brain, myocardium, and liver was assessed by laser Doppler flowmetry using LAKK-OP2 and LAZMA-D computerized laser analyzers. Using spectral wavelet analysis, we determined the absolute and normalized to total perfusion amplitudes of microcirculation oscillations reflecting various regulatory mechanisms. Intact animals served as controls. In rats of the experimental group, alcoholic cardiomyopathy completely developed. Under these conditions, the index of microcirculation in the brain, myocardium, and liver significantly decreased. At the same time, there was a redistribution in the brain between shunting and nutritive blood flow in favor of the latter. In the myocardium and liver, this ratio did not change.

Indexed as

Cardiomyopathy, AlcoholicAnimalsBrainFemaleHeartLaser-Doppler FlowmetryLiverMicrocirculationRatsalcoholic cardiomyopathyechocardiographyfemale ratslaser Doppler flowmetrymicrocirculation

Identifiers

PMID37770783
OpenAlexW4387127650

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.