SynthesisTranslational psychiatry2023
Psychological interventions for the prevention of depression relapse: systematic review and network meta-analysis.
Synthesis in Translational psychiatry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.
- Bibliometric analysis of trends, innovations, and the future of CBT-based mobile interventions for depression.Frontiers in medicine · 2025Pooled it
- Repetitive Transcranial Magnetic Stimulation as Maintenance Treatment of Depression: The MAINT-R Randomized Clinical Trial.JAMA network open · 2025Trial
- Development and evaluation of an intervention package to alleviate the psychological effects of premenstrual syndrome in adolescent girls.BMC women's health · 2025Trial
- The Thought Induction Psychotherapy Technique's Clinical Effectiveness in Treating Adolescent Depression and Anxiety: A Randomized Controlled Trial.Psychiatry investigation · 2026Article
- Cost-Effectiveness and Impact of Depression Treatment Implementation on HIV Outcomes in Western Kenya: A Mathematical Modelling Study.Journal of the International AIDS Society · 2026Article
- Conversational AI should fill the white space in mental health care, not replace humans.NPJ digital medicine · 2026Review
- Systematic review on relapse-prevention strategies following successful electroconvulsive therapy for major depressive disorder.BJPsych open · 2026Review
- Remodeling the tumor dormancy ecosystem to prevent recurrence and metastasis.Signal transduction and targeted therapy · 2026Review
- The Self-Identification Program (SIP): A Clinically Implemented Third-Wave CBT Deepening Dysfunctional Self-Identification in Mood Disorders.Medicina (Kaunas, Lithuania) · 2025Article
- Complex Intervention Programs Integrating Multiple Intervention Strategies Were Not More Effective than Active Control Groups: Evidence from Randomized Controlled Trials.Behavioral sciences (Basel, Switzerland) · 2025Article
- Bibliometric and visual analysis of circadian rhythms in depression from 2004 to 2024.Annals of general psychiatry · 2025Article
- Understanding the nature and dynamics of self-affirmation in non-depressed and subclinically depressed Indian adults: a thematic analysis.BMC psychiatry · 2025Article
- Acceptance and Commitment Therapy for Major Depressive Disorder: Navigating Depression Treatment in Traditional and Digital Settings with Insights from Current Research.Advances in experimental medicine and biology · 2024Review
Corrections and comments
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Authors and funding
14 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Depression is highly prevalent and easily relapses. Psychological interventions are effective for the prevention of depression relapse. This systematic review and network meta-analysis aimed to compare the efficacy at the same follow-up time points of psychological interventions in depression. We searched PubMed, Embase, and PsycINFO via OVID, and the Cochrane Library published up to December 12, 2021, and PubMed up to July 1, 2022. The primary outcome was depression relapse, considering the same time points that were extracted on survival curves or relapse curves. The study protocol was registered with PROSPERO, CRD42022343327. A total of 2,871 patients were included from 25 RCTs. Mindfulness-based cognitive therapy (MBCT) was significantly better than placebo at the 3 months, the 6 months, and the 9 months at follow-up. Cognitive behavioral therapy (CBT) was significantly better than treatment as usual at the 3 months, the 9 months, the 12 months, and the 15 months at follow-up. CBT was significantly better than placebo at the 21 months and the 24 months at follow-up. Behavioral activation therapy was significantly better than placebo at the 21 months and the 24 months at follow-up. Interpersonal psychotherapy was significantly better than placebo at the 24-month follow-up. All psychological interventions included in the study were significantly better than supportive counseling most of the time. The results were robust in various sensitivity and subgroup analyses. In conclusion, MBCT had a continuous effect in preventing relapse of depression. CBT had the longest but not continuous effect in preventing relapse of depression. The effects of behavioral activation therapy and interpersonal therapy for the prevention of depression appeared late. All psychological interventions included in the study were more effective than supportive counseling. More evidence is needed from large comparative trials that provide long-term follow-up data.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.