ArticleNature communications2023
Synthesis of a covalent organic framework with hetero-environmental pores and its medicine co-delivery application.
Article in Nature communications, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Porphyrin-Based Porous Materials for Antibacterial Applications.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Review
- 3D Liquid Crystal Framework Enclosing Dual Compartments.Angewandte Chemie (International ed. in English) · 2026Article
- Amine-linked heteroporous covalent organic framework for synergistic anti-infective therapy of post-traumatic osteomyelitis.Nature communications · 2026Article
- An AI-assisted designed supramolecularly engineered nanoplatform reverses pigmentation by triggering an ineffective compensatory melanin production program.Bioactive materials · 2026Article
- MitoSiege-Driven Catalase Collapse: A GSH-Responsive, Mitochondria-Targeted COF Prodrug for Amplified Chemodynamic Therapy.Angewandte Chemie (International ed. in English) · 2025Article
- Icariin delivery system based on covalent organic framework materials: dual effects of immune modulation and osteogenesis promotion.RSC advances · 2025Article
- Glucose oxidase: An emerging multidimensional treatment option for diabetic wound healing.Bioactive materials · 2025Review
- Social Self-Sorting of Quasi-Racemates: A Unique Approach for Dual-Pore Molecular Crystals.Journal of the American Chemical Society · 2024Article
- Regulation of metabolic microenvironment with a nanocomposite hydrogel for improved bone fracture healing.Bioactive materials · 2024Article
- Creating amphiphilic porosity in two-dimensional covalent organic frameworks via steric-hindrance-mediated precision hydrophilic-hydrophobic microphase separation.Nature communications · 2024Article
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Authors and funding
10 authors.
Funding
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Abstract
The topology type and the functionalization of pores play an important role in regulating the performance of covalent organic frameworks. Herein, we designed and synthesized the covalent organic framework with hetero-environmental pores using predesigned asymmetrical dialdehyde monomer. According to the results of structural characterization, crystallinity investigation, and theoretical calculation, the hetero-environmental pores of the obtained framework are regarded as the alternant arrangement. The distinctive hetero pore structure leads the designed material to show more advantages as compared with control materials in loading both hydrophobic and hydrophilic antibiotics for wound healing. This dual-antibiotic strategy can expand the antibacterial range as compared with the single antibiotic one, and reduce the generation of drug resistance. In summary, this strategy for designing covalent organic frameworks with hetero-environmental pores can extend the structural variety and provide a pathway for improving the practical application performance of these materials.
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