Evidence map›Paper›PMID 37770349›Full record

ArticleThe American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry2024

Hoarding Symptoms in Late Life Depression are Associated With Greater Executive Dysfunction and Disability and Poorer Response to Depression Treatment.

Michelle T Kassel, Maria Kryza-Lacombe, Philip S Insel, Emma Rhodes, Derek D Satre, J Craig Nelson, Duygu Tosun, Carol A Mathews, R Scott Mackin

Open access · bronzeAbstract read
In one paragraph

Article in The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Trial
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Michelle T KasselMental Illness Research, Education, and Clinical Centers (MTK, MKL, ER, RSM), San Francisco Veterans Affairs Health Care System, San Francisco, CA; Department of Psychiatry and Behavioral Sciences (MTK, MKL, PSI, ER, DDS, JCN, RSM), University of California San Francisco, San Francisco, CA. Electronic address: michelle.kassel@ucsf.edu.
Maria Kryza-LacombeMental Illness Research, Education, and Clinical Centers (MTK, MKL, ER, RSM), San Francisco Veterans Affairs Health Care System, San Francisco, CA; Department of Psychiatry and Behavioral Sciences (MTK, MKL, PSI, ER, DDS, JCN, RSM), University of California San Francisco, San Francisco, CA.
Philip S InselDepartment of Psychiatry and Behavioral Sciences (MTK, MKL, PSI, ER, DDS, JCN, RSM), University of California San Francisco, San Francisco, CA.
Emma RhodesMental Illness Research, Education, and Clinical Centers (MTK, MKL, ER, RSM), San Francisco Veterans Affairs Health Care System, San Francisco, CA; Department of Psychiatry and Behavioral Sciences (MTK, MKL, PSI, ER, DDS, JCN, RSM), University of California San Francisco, San Francisco, CA.
Derek D SatreDepartment of Psychiatry and Behavioral Sciences (MTK, MKL, PSI, ER, DDS, JCN, RSM), University of California San Francisco, San Francisco, CA; Division of Research (DDS), Kaiser Permanente Northern California, Oakland, CA.
J Craig NelsonDepartment of Psychiatry and Behavioral Sciences (MTK, MKL, PSI, ER, DDS, JCN, RSM), University of California San Francisco, San Francisco, CA.
Duygu TosunDepartment of Radiology and Biomedical Imaging (DT), University of California San Francisco, San Francisco, CA.
Carol A MathewsDepartment of Psychiatry and Center for OCD, Anxiety and Related Disorders (CAM), University of Florida, Gainesville, FL.
R Scott MackinMental Illness Research, Education, and Clinical Centers (MTK, MKL, ER, RSM), San Francisco Veterans Affairs Health Care System, San Francisco, CA; Department of Psychiatry and Behavioral Sciences (MTK, MKL, PSI, ER, DDS, JCN, RSM), University of California San Francisco, San Francisco, CA.
University of California, San Francisco · USKaiser Permanente · USSan Francisco VA Health Care System · USUniversity of Florida · US

Funding

Predicting populations at-risk of developing pathological hoardingR01MH117114 · NIMH · UNIVERSITY OF FLORIDA · PI MACKIN, ROBERT SCOTT, MATHEWS, CAROL A · 2018 to 2022
$3.7M
Multimodal MRI Characteristics of Psychotherapy Response in Late Life DepressionR01MH101472 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MACKIN, ROBERT SCOTT, TOSUN-TURGUT, DUYGU · 2015 to 2019
$3.3M
Mentoring alcohol use intervention research in HIV health care settingsK24AA025703 · NIAAA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Derek D Satre · 2018 to 2026
$1.8M
Digital monitoring of autonomic activity to detect empathy loss in behavioral variant frontotemporal dementiaK23AG083124 · NIA · UNIVERSITY OF PENNSYLVANIA · PI Emma Rhodes · 2023 to 2026
$652k
NIAAA NIH HHS K24 AA025703NIA NIH HHS K23 AG083124NIMH NIH HHS R01 MH101472NIMH NIH HHS R01 MH117114
6 · The paper itself

Abstract

objectivesLate life depression (LLD) and hoarding disorder (HD) are common in older adults and characterized by executive dysfunction and disability. We aimed to determine the frequency of co-occurring HD in LLD and examine hoarding severity as an additional contributor to executive dysfunction, disability, and response to psychotherapy for LLD.

designCross-sectional.

settingOutpatient psychiatry program.

participantsEighty-three community-dwelling adults ages 65-90 with LLD.

interventionProblem-solving therapy. MEASUREMENTS: Measures of executive function, disability, depression, and hoarding severity were completed at post-treatment. Pearson's chi-squared tests evaluated group differences in rates of cognitive impairment, disability, and depression treatment response between participants with HD (LLD+HD) and LLD only. Separate linear regressions assessed associations between hoarding severity and executive function, disability, and psychotherapy response. Covariates included age, education, gender, and depression severity.

results30.1% (25/83) of LLD participants met HD criteria. Relative to LLD, LLD+HD participants demonstrated greater impairment rates on measures of executive function (Letter-Number-Sequencing, X

conclusionsWe found 30.1% co-occurrence of HD in LLD, which was accompanied by greater executive dysfunction, disability, and poorer response to depression treatment. Results underscore the need for increased screening of hoarding behaviors in LLD and tailored interventions for this LLD+HD group.

Indexed as

Cognitive DysfunctionHoardingHoarding DisorderAgedCompulsive BehaviorCross-Sectional StudiesDepressionHumansdisabilityexecutive functionhoardingLate life depressionpsychotherapytreatment response

Identifiers

PMID37770349
PMCPMC10872841
OpenAlexW4386379290

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.