Evidence map›Paper›PMID 37770262›Full record

Observational studyBMJ open2023

Robotic and laparoscopic gynaecological surgery: a prospective multicentre observational cohort study and economic evaluation in England.

Andrew McCarthy, Dilupa Samarakoon, Joanne Gray, Peter Mcmeekin, Stephen McCarthy, Claire Newton, Marielle Nobbenhuis, Jonathan Lippiatt, Jeremy Twigg

Open access · goldAbstract readObservational StudyMulticenter Study
In one paragraph

Observational study in BMJ open, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
1.8field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Article
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  8. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Andrew McCarthyDepartment of Nursing, Midwifery and Health, Northumbria University, Newcastle upon Tyne, UK andrew2.mccarthy@northumbria.ac.uk.ORCID 0000-0002-3385-6302
Dilupa SamarakoonDepartment of Nursing, Midwifery and Health, Northumbria University, Newcastle upon Tyne, UK.
Joanne GrayDepartment of Nursing, Midwifery and Health, Northumbria University, Newcastle upon Tyne, UK.
Peter McmeekinDepartment of Nursing, Midwifery and Health, Northumbria University, Newcastle upon Tyne, UK.
Stephen McCarthyDepartment of Nursing, Midwifery and Health, Northumbria University, Newcastle upon Tyne, UK.
Claire NewtonDepartment of Gynaecology Oncology, University Hospitals Bristol and Weston NHS Foundation Trust, Bristol, UK.
Marielle NobbenhuisDepartment of Gynaecological Oncology, Royal Marsden NHS Foundation Trust, London, UK.
Jonathan LippiattDepartment of Gynaecological Oncology, University Hospitals Dorset NHS Foundation Trust, Poole, UK.
Jeremy TwiggDepartment of Gynaecological Oncology, Coventry and Warwickshire Hospital, Coventry, UK.
Northumbria University · GBPoole Hospital · GBRoyal Marsden NHS Foundation Trust · GBUniversity Hospitals Bristol NHS Foundation Trust · GBWarwickshire Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo compare the health-related quality of life and cost-effectiveness of robot-assisted laparoscopic surgery (RALS) versus conventional 'straight stick' laparoscopic surgery (CLS) in women undergoing hysterectomy as part of their treatment for either suspected or proven gynaecological malignancy.

designMulticentre prospective observational cohort study.

settingPatients aged 16+ undergoing hysterectomy as part of their treatment for gynaecological malignancy at 12 National Health Service (NHS) cancer units and centres in England between August 2017 and February 2020.

participants275 patients recruited with 159 RALS, 73 CLS eligible for analysis. OUTCOME MEASURES: Primary outcome was the European Organisation for Research and Treatment of Cancer Quality of Life measure (EORTC). Secondary outcomes included EuroQol-5 Dimension (EQ-5D-5L) utility, 6-minute walk test (6MWT), NHS costs using pounds sterling (£) 2018-2019 prices and cost-effectiveness. The cost-effectiveness evaluation compared EQ-5D-5L quality adjusted life years and costs between RALS and CLS.

resultsNo difference identified between RALS and CLS for EORTC, EQ-5D-5L utility and 6MWT. RALS had unadjusted mean cost difference of £556 (95% CI -£314 to £1315) versus CLS and mean quality adjusted life year (QALY) difference of 0.0024 (95% CI -0.00051 to 0.0057), non-parametric incremental cost-effectiveness ratio of £231 667per QALY. For the adjusted cost-effectiveness analysis, RALS dominated CLS with a mean cost difference of -£188 (95% CI -£1321 to £827) and QALY difference of 0.0024 (95% CI -0.0008 to 0.0057).

conclusionsFindings suggest that RALS versus CLS in women undergoing hysterectomy (after adjusting for differences in morbidity) is cost-effective with lower costs and QALYs. Results are highly sensitive to the usage of robotic hardware with higher usage increasing the probability of cost-effectiveness. Non-inferiority randomised controlled trial would be of benefit to decision-makers to provide further evidence on the cost-effectiveness of RALS versus CLS but may not be practical due to surgical preferences of surgeons and the extensive roll out of RALS.

Indexed as

Genital Neoplasms, FemaleLaparoscopyRoboticsRobotic Surgical ProceduresCost-Benefit AnalysisEnglandFemaleHumansHysterectomyProspective StudiesQuality-Adjusted Life YearsQuality of LifeState Medicinegynaecological oncologyhealth economicsminimally invasive surgery

Identifiers

PMID37770262
PMCPMC10546163
OpenAlexW4387143152

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.