Evidence map›Paper›PMID 37770127›Full record

ArticleGut2023

Winnie Fong, Qing Li, Fenfen Ji, Wei Liang, Harry Cheuk Hay Lau, Xing Kang, Weixin Liu, Kenneth Kin-Wah To, Zhong Zuo, Xiaoxing Li and 3 more

Open access · hybridAbstract read
In one paragraph

Article in Gut, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 193 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
193citing papers in PubMed, 3 pooled it
22.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

193 citing papers in PubMed, 3 syntheses or guidelines pooled it, 229 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Review
  6. Review
  7. Review
  8. Article
  9. Review
  10. Article
  11. Gut Microbial Topology and Metabolic Signatures Associated With Colorectal Neoplasia.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  12. Review
  13. Article
  14. Review
  15. Review
  16. Review
  17. Review
  18. Evolution of SPP1Cell reports. Medicine · 2026
    Article
  19. Low-Dose Intestinal Irradiation Enhances the Efficacy and Prognosis of PD-1 Blockade in Metastatic Non-Small Cell Lung Cancer.Clinical cancer research : an official journal of the American Association for Cancer Research · 2026
    Article
  20. Gut microbiota modulation of systemic immunity and cancer immunotherapy: mechanisms, evidence, and therapeutic implications.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2026
    Review

133 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 5 countries.

Winnie FongInstitute of Digestive Disease, Department of Medicine and Therapeutics, State Key Laboratory of Digestive Disease, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong, China.
Qing LiInstitute of Digestive Disease, Department of Medicine and Therapeutics, State Key Laboratory of Digestive Disease, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong, China.
Fenfen JiInstitute of Digestive Disease, Department of Medicine and Therapeutics, State Key Laboratory of Digestive Disease, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong, China.
Wei LiangInstitute of Precision Medicine, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China.
Harry Cheuk Hay LauInstitute of Digestive Disease, Department of Medicine and Therapeutics, State Key Laboratory of Digestive Disease, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong, China.ORCID 0000-0003-3581-2909
Xing KangInstitute of Digestive Disease, Department of Medicine and Therapeutics, State Key Laboratory of Digestive Disease, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong, China.
Weixin LiuInstitute of Digestive Disease, Department of Medicine and Therapeutics, State Key Laboratory of Digestive Disease, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong, China.
Kenneth Kin-Wah ToSchool of Pharmacy, The Chinese University of Hong Kong, Hong Kong, China.
Zhong ZuoSchool of Pharmacy, The Chinese University of Hong Kong, Hong Kong, China.
Xiaoxing LiInstitute of Precision Medicine, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China.ORCID 0000-0001-8791-7505
Xiang ZhangInstitute of Digestive Disease, Department of Medicine and Therapeutics, State Key Laboratory of Digestive Disease, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong, China.
Joseph Jy SungLee Kong Chian School of Medicine, Nanyang Technological University, Singapore.ORCID 0000-0003-3125-5199
Jun YuInstitute of Digestive Disease, Department of Medicine and Therapeutics, State Key Laboratory of Digestive Disease, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong, China junyu@cuhk.edu.hk.ORCID 0000-0001-5008-2153
Chinese University of Hong Kong · HKSun Yat-sen University · CNNanyang Technological University · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveGut microbiota is a key player in dictating immunotherapy response. We aimed to explore the immunomodulatory effect of probiotic

designThe effects of

results

conclusion

Indexed as

Colorectal NeoplasmsImmune Checkpoint InhibitorsKynurenineLactobacillusAnimalsBacterial LysatesCD8-Positive T-LymphocytesIndoleamine-Pyrrole 2,3,-DioxygenaseMiceProgrammed Cell Death 1 ReceptorReceptors, Aryl HydrocarbonT-Lymphocytes, RegulatoryBacterial LysatesIDO1 protein, mouseImmune Checkpoint InhibitorsIndoleamine-Pyrrole 2,3,-DioxygenaseKynureninePdcd1 protein, mouseProgrammed Cell Death 1 ReceptorReceptors, Aryl Hydrocarboncolorectal cancerimmunotherapyprobiotics

Identifiers

PMID37770127
PMCPMC10715476
OpenAlexW4387141604

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.