ArticleThe Plant cell2023
H2O2-dependent oxidation of the transcription factor GmNTL1 promotes salt tolerance in soybean.
Article in The Plant cell, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 34 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed, 73 citations in OpenAlex.
- Exogenous N-Acetyl-L-cysteine Improves Soybean Saline-Alkali Tolerance by Enhancing the hGSH Pathway to Alleviate Oxidative Damage.Plants (Basel, Switzerland) · 2026Article
- Decoding stress resilience in soybean: Regulatory networks and precision breeding under climate change.Journal of integrative plant biology · 2026Review
- Key metabolites secreted by Chlorella vulgaris alleviate salt stress in soybean seedlings.Journal of integrative plant biology · 2026Article
- Genome-Wide Identification and Characterization of NAC Transcription Factors in Avocado (Genes · 2026Article
- Comprehensive analysis of maBIOTECH · 2026Article
- Hydrogen Sulfide Primes bZIP68 via Persulfidation to Enhance Redox-Dependent Transcription and Adaptation to Osmotic Stress in Rice.International journal of molecular sciences · 2026Article
- Fulvic Acid Suppresses Excessive Cytokinin Biosynthesis to Reduce ROS Content and thus Decrease NaRice (New York, N.Y.) · 2026Article
- Article
- A Novel GmSIN1-GmRNF1a-GmCSN5a Module Determines Soybean Salt Tolerance and Yield Under Saline Soil Conditions.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Genome-Wide Analysis of the DUF1664 Family Genes in Peanut (Plants (Basel, Switzerland) · 2026Article
- Natural Variation of a PPR Coding Gene SST1 Confers Salt Tolerance During Soybean Domestication.Plant biotechnology journal · 2026Article
- New progress in the production, oxidative damage, and scavenging mechanisms of reactive oxygen species in plants under abiotic stress.Frontiers in plant science · 2026Review
- Protein Post-Translational Modifications in Plant Abiotic Stress Responses.Plants (Basel, Switzerland) · 2025Review
- Screening of salt-tolerant alfalfa germplasm and study of salt-tolerance mechanism.Plant cell reports · 2025Article
- Salt Tolerance in Soybean (Plants (Basel, Switzerland) · 2025Review
- Advances in deciphering the mechanisms of salt tolerance in Maize.Plant signaling & behavior · 2025Review
- Identification of the Splicing FactorInternational journal of molecular sciences · 2025Article
- OsNTL2 confers rice osmotic stress resilience through coordinated transcriptional regulation of the ASC-GSH redox cycle and cell wall biosynthesis.Stress biology · 2025Article
- A Coding SNP in GmPM30 Enhances Soybean Salinity Tolerance and Yield through the GmLEA1-GmPM30-GmLEC1 Module.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Article
Corrections and comments
- Erratum issued
Authors and funding
15 authors at 2 institutions in 2 countries.
Funding
Abstract
Reactive oxygen species (ROS) play an essential role in plant growth and responses to environmental stresses. Plant cells sense and transduce ROS signaling directly via hydrogen peroxide (H2O2)-mediated posttranslational modifications (PTMs) on protein cysteine residues. Here, we show that the H2O2-mediated cysteine oxidation of NAC WITH TRANS-MEMBRANE MOTIF1-LIKE 1 (GmNTL1) in soybean (Glycine max) during salt stress promotes its release from the endoplasmic reticulum (ER) membrane and translocation to the nucleus. We further show that an oxidative posttranslational modification on GmNTL1 residue Cys-247 steers downstream amplification of ROS production by binding to and activating the promoters of RESPIRATORY BURST OXIDASE HOMOLOG B (GmRbohB) genes, thereby creating a feed-forward loop to fine-tune GmNTL1 activity. In addition, oxidation of GmNTL1 Cys-247 directly promotes the expression of CATION H+ EXCHANGER 1 (GmCHX1)/SALT TOLERANCE-ASSOCIATED GENE ON CHROMOSOME 3 (GmSALT3) and Na+/H+ Antiporter 1 (GmNHX1). Accordingly, transgenic overexpression of GmNTL1 in soybean increases the H2O2 levels and K+/Na+ ratio in the cell, promotes salt tolerance, and increases yield under salt stress, while an RNA interference-mediated knockdown of GmNTL1 elicits the opposite effects. Our results reveal that the salt-induced oxidation of GmNTL1 promotes its relocation and transcriptional activity through an H2O2-mediated posttranslational modification on cysteine that improves resilience of soybean against salt stress.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.