Evidence map›Paper›PMID 37769138›Full record

ReviewRevista medica del Instituto Mexicano del Seguro Social2023

[Potential use of liposomes in tuberculosis treatment].

Yolanda Monserrath Jacobo-Delgado, Gabriela Navarro-Tovar, Bruno Rivas-Santiago

Abstract readEnglish AbstractReview
In one paragraph

Review in Revista medica del Instituto Mexicano del Seguro Social, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Yolanda Monserrath Jacobo-DelgadoInstituto Mexicano del Seguro Social, Hospital General de Zona No. 1 "Dr. Emilio Varela Lujan", Unidad de Investigación Biomédica de Zacatecas. Zacatecas, Zacatecas, México.ORCID 0000-0003-2174-6277
Gabriela Navarro-TovarUniversidad Autónoma de San Luís Potosí, Facultad de Ciencias Químicas, Posgrado en Ciencias Farmacobiológicas. San Luis Potosí, San Luis Potosí, México.ORCID 0000-0003-3789-2324
Bruno Rivas-SantiagoInstituto Mexicano del Seguro Social, Hospital General de Zona No. 1 "Dr. Emilio Varela Lujan", Unidad de Investigación Biomédica de Zacatecas. Zacatecas, Zacatecas, México.ORCID 0000-0002-1521-1519

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tuberculosis is among the infectious diseases with the highest mortality and morbidity worldwide, behind the COVID-19 pandemic. It can affect any organ, although the respiratory infection is the most common. The correct activation of the immune response eliminates or contain the bacteria; however, the active disease is progressive and must be treated under strict supervision. Treatment for tuberculosis is prolonged and consists of a combination of several antibiotics associated with a wide variety of adverse effects. These effects are the main cause of therapeutic abandonment, which facilitates the appearance of drug-resistant strains. Hence the importance of developing new therapeutic strategies to reduce the dose of the drug or its administration time. To achieve these objectives, the use of nano-vehicles, which are controlled and directed drug release systems, has been proposed. Specifically, liposomes are formulations that have advantages when administered by the respiratory route since they facilitate the reach of the respiratory mucosa and the lungs, which are the main organs affected by tuberculosis. This review analyzes the use of nano-vehicles as effective drug delivery systems and the formulations under study. Perspectives for the application of nanotechnology in the development of new pharmacological treatments for tuberculosis are also proposed.

Indexed as

COVID-19TuberculosisAntitubercular AgentsHumansLiposomesPandemicsAntitubercular AgentsLiposomesDrug Resistance, MicrobialLiposomesTuberculosis

Identifiers

PMID37769138
PMCPMC10599776

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.