Article in ACS chemical biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literature
Who cites it
4 citing papers in PubMed, 6 citations in OpenAlex.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
16 authors at 5 institutions in 2 countries.
Jaroslava ŠeflováDepartment of Cell and Molecular Physiology, Loyola University Chicago, Chicago, Illinois 60153, United States.
Jacob A SchwarzDepartment of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, Minnesota 55455, United States.
Abigail N SmithDepartment of Chemistry & Vanderbilt Institute of Chemical Biology, Vanderbilt University, Nashville, Tennessee 37235, United States.ORCID 0000-0003-0921-1835
Bengt SvenssonDepartment of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, Minnesota 55455, United States.ORCID 0000-0003-3932-2376
Daniel J BlackwellDepartment of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee 37232, United States.
Taylor A PhillipsDepartment of Cell and Molecular Physiology, Loyola University Chicago, Chicago, Illinois 60153, United States.
Roman NikolaienkoDepartment of Cell and Molecular Physiology, Loyola University Chicago, Chicago, Illinois 60153, United States.ORCID 0000-0002-9836-2880
Elisa BovoDepartment of Cell and Molecular Physiology, Loyola University Chicago, Chicago, Illinois 60153, United States.
Robyn T RebbeckDepartment of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, Minnesota 55455, United States.
Aleksey V ZimaDepartment of Cell and Molecular Physiology, Loyola University Chicago, Chicago, Illinois 60153, United States.ORCID 0000-0001-7280-2924
David D ThomasDepartment of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, Minnesota 55455, United States.ORCID 0000-0002-8822-2040
Filip Van PetegemDepartment of Biochemistry and Molecular Biology, Life Sciences Centre, University of British Columbia, Vancouver, British Columbia V6T 1Z3, Canada.
Björn C KnollmannDepartment of Chemistry & Vanderbilt Institute of Chemical Biology, Vanderbilt University, Nashville, Tennessee 37235, United States.
Jeffrey N JohnstonDepartment of Chemistry & Vanderbilt Institute of Chemical Biology, Vanderbilt University, Nashville, Tennessee 37235, United States.ORCID 0000-0002-0885-636X
Seth L RobiaDepartment of Cell and Molecular Physiology, Loyola University Chicago, Chicago, Illinois 60153, United States.ORCID 0000-0002-1193-9510
Răzvan L CorneaDepartment of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, Minnesota 55455, United States.ORCID 0000-0001-5739-0992
Loyola University Chicago · USUniversity of Minnesota · USVanderbilt University · USUniversity of British Columbia · CAVanderbilt University Medical Center · US
Funding
Pathophysiological Regulation of Cardiac Myocyte RyR ChannelR01HL092097 · NHLBI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI Donald M Bers, Robyn T Rebbeck · 2010 to 2026
$9.3M
Development of a Mirror-Image Natural Product as an Antiarrhythmic TherapeuticR01HL151223 · NHLBI · VANDERBILT UNIVERSITY · PI JOHNSTON, JEFFREY NICHOLAS · 2020 to 2023
$3.1M
High-Throughput Screens to Discover Novel Inhibitors of Leaky RyR2 for Heart Failure TherapyR01HL138539 · NHLBI · UNIVERSITY OF MINNESOTA · PI BERS, DONALD M, CORNEA, RAZVAN LIVIU · 2018 to 2021
$3.1M
The NKA Interactome in Health and DiseaseR01HL158649 · NHLBI · LOYOLA UNIVERSITY CHICAGO · PI BOSSUYT, JULIE B, ROBIA, SETH L · 2022 to 2025
$2.7M
New mechanisms of SERCA2a regulation: role of luminal calciumR01HL151990 · NHLBI · LOYOLA UNIVERSITY CHICAGO · PI ZIMA, ALEKSEY V · 2021 to 2024
$1.7M
Development of Ryanodine Receptor 2 Selective ProbesF31HL151125 · NHLBI · VANDERBILT UNIVERSITY · PI SMITH, ABIGAIL · 2020 to 2021
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
RyR2 Binding of an Antiarrhythmic Cyclic Depsipeptide Mapped Using Confocal Fluorescence Lifetime Detection of FRET. · full record | OpenQuestion