Evidence map›Paper›PMID 37768824›Full record

ArticleCell reports2023

Low dietary fiber intake impairs small intestinal Th17 and intraepithelial T cell development over generations.

Charlotte J Royer, Naomi Rodriguez-Marino, Madelyn D Yaceczko, Dormarie E Rivera-Rodriguez, Thomas R Ziegler, Luisa Cervantes-Barragan

Open access · goldAbstract read
In one paragraph

Article in Cell reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Charlotte J RoyerDepartment of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA 30322, USA.
Naomi Rodriguez-MarinoDepartment of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA 30322, USA.
Madelyn D YaceczkoDepartment of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA 30322, USA.
Dormarie E Rivera-RodriguezDepartment of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA 30322, USA; Emory Vaccine Center, Emory University School of Medicine, Atlanta, GA 30322, USA; Division of Infectious Diseases, Emory University School of Medicine, Atlanta, GA 30322, USA.
Thomas R ZieglerDivision of Endocrinology, Metabolism, and Lipids and Center for Clinical and Molecular Nutrition, Department of Medicine, Emory University School of Medicine, Atlanta, GA 30322, USA.
Luisa Cervantes-BarraganDepartment of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA 30322, USA. Electronic address: lcervantes@emory.edu.
Emory University · US

Funding

Implementing a Maternal health and PRegnancy Outcomes Vision for Everyone (IMPROVE)UL1TR002378 · NCATS · EMORY UNIVERSITY · PI Andres J Garcia, Elizabeth O. Ofili · 2017 to 2026
$92.1M
Antimicrobial Resistance and Therapeutic Discovery Training ProgramT32AI106699 · NIAID · EMORY UNIVERSITY · PI Graeme L Conn, Joanna B Goldberg · 2014 to 2026
$2.7M
Role of dietary fiber-microbiota Interactions in the development and function of small intestinal T cellsR01DK129950 · NIDDK · EMORY UNIVERSITY · PI CERVANTES BARRAGAN, LUISA · 2021 to 2025
$2.4M
NCATS NIH HHS UL1 TR002378NIAID NIH HHS T32 AI106699NIDDK NIH HHS R01 DK129950
6 · The paper itself

Abstract

Dietary fiber strongly impacts the microbiota. Here, we show that a low-fiber diet changes the small intestinal (SI) microbiota and impairs SI Th17, TCRαβ

Indexed as

Gastrointestinal MicrobiomeIntraepithelial LymphocytesMicrobiotaAnimalsDietary FiberIntestinal MucosaIntestine, SmallMiceMice, Inbred C57BLReceptors, Antigen, T-Cell, alpha-betaDietary FiberReceptors, Antigen, T-Cell, alpha-betaCD8αβ(+) IELCP: ImmunologyCP: Microbiologydietary fiberIEL T cellsinterleukin 17intraepithelialmicrobiotasegmented filamentous bacteriaTh17

Identifiers

PMID37768824
PMCPMC10765424
OpenAlexW4387111965

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.