Evidence map›Paper›PMID 37768558›Full record

ArticleEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin2023

Increased reports of severe myocarditis associated with enterovirus infection in neonates, United Kingdom, 27 June 2022 to 26 April 2023.

Anika Singanayagam, Catherine Moore, Susannah Froude, Cristina Celma, Julia Stowe, Erjola Hani, Khuen Foong Ng, Peter Muir, Marion Roderick, Simon Cottrell and 24 more

Open access · diamondAbstract read
In one paragraph

Article in Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
4.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 21 citations in OpenAlex.

  1. Review
  2. Enterovirus infections in children.Pediatric investigation · 2026
    Review
  3. Article
  4. Article
  5. Article
  6. Enhancing detection of severe enterovirus infections: A data linkage study of ICD-10 codes with national enterovirus laboratory data, Denmark, 2010 to 2023.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2026
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. [Neonatal myocarditis due to Coxsackie: case report and literature review].Revista medica del Instituto Mexicano del Seguro Social · 2024
    Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

34 authors at 6 institutions in 1 country.

Anika SinganayagamUK Health Security Agency, Colindale, London, United Kingdom.
Catherine MoorePublic Health Wales, Wales, Cardiff, United Kingdom.
Susannah FroudePublic Health Wales, Wales, Cardiff, United Kingdom.
Cristina CelmaUK Health Security Agency, Colindale, London, United Kingdom.
Julia StoweUK Health Security Agency, Colindale, London, United Kingdom.
Erjola HaniUK Health Security Agency, Colindale, London, United Kingdom.
Khuen Foong NgPaediatric Infectious Diseases and Immunology, Bristol Royal Hospital for Children, Bristol, United Kingdom.
Peter MuirUK Health Security Agency South West Regional Laboratory, Bristol, United Kingdom.
Marion RoderickPaediatric Infectious Diseases and Immunology, Bristol Royal Hospital for Children, Bristol, United Kingdom.
Simon CottrellPublic Health Wales, Wales, Cardiff, United Kingdom.
David F BibbyUK Health Security Agency, Colindale, London, United Kingdom.
Barry VipondUK Health Security Agency South West Regional Laboratory, Bristol, United Kingdom.
Sophie GillettUK Health Security Agency South West Regional Laboratory, Bristol, United Kingdom.
Peter J DavisPaediatric Intensive Care Unit, Bristol Royal Hospital for Children, University Hospitals Bristol & Weston Foundation Trust, Bristol, United Kingdom.
Jack GibbDepartment of Paediatric Cardiology, Bristol Royal Hospital for Children, University Hospitals Bristol & Weston Foundation Trust, Bristol, United Kingdom.
Mai BarryPublic Health Wales, Wales, Cardiff, United Kingdom.
Phillippa HarrisPublic Health Wales, Wales, Cardiff, United Kingdom.
Frances RowleyPublic Health Wales, Wales, Cardiff, United Kingdom.
Jiao SongPublic Health Wales, Wales, Cardiff, United Kingdom.
Ananda Giri ShankarPublic Health Wales, Wales, Cardiff, United Kingdom.
Danielle McMichaelPublic Health Agency, Belfast, United Kingdom.
Jonathan M CohenEvelina London Children's Hospital, Guys & St Thomas National Health Service Foundation Trust, London, United Kingdom.
Abirami ManianEvelina London Children's Hospital, Guys & St Thomas National Health Service Foundation Trust, London, United Kingdom.
Ciaran HarveyPublic Health Scotland, Glasgow, United Kingdom.
Louise Shaw PrimrosePublic Health Scotland, Glasgow, United Kingdom.
Stefanie WilsonPublic Health Scotland, Glasgow, United Kingdom.
Declan T BradleyPublic Health Agency, Belfast, United Kingdom.
Karthik ParanthamanUK Health Security Agency, Colindale, London, United Kingdom.
Stuart BeardUK Health Security Agency, Colindale, London, United Kingdom.
Maria ZambonUK Health Security Agency, Colindale, London, United Kingdom.
Mary RamsayUK Health Security Agency, Colindale, London, United Kingdom.
Vanessa SalibaUK Health Security Agency, Colindale, London, United Kingdom.
Shamez LadhaniUK Health Security Agency, Colindale, London, United Kingdom.
Christopher WilliamsPublic Health Wales, Wales, Cardiff, United Kingdom.
UK Health Security Agency · GBPublic Health Wales · GBBristol Royal Hospital for Children · GBPublic Health Scotland · GBNational Health Service · GBPublic Health Agency · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Enteroviruses are a common cause of seasonal childhood infections. The vast majority of enterovirus infections are mild and self-limiting, although neonates can sometimes develop severe disease. Myocarditis is a rare complication of enterovirus infection. Between June 2022 and April 2023, twenty cases of severe neonatal enteroviral myocarditis caused by coxsackie B viruses were reported in the United Kingdom. Sixteen required critical care support and two died. Enterovirus PCR on whole blood was the most sensitive diagnostic test. We describe the initial public health investigation into this cluster and aim to raise awareness among paediatricians, laboratories and public health specialists.

Indexed as

EnterovirusEnterovirus InfectionsMyocarditisChildEnterovirus B, HumanHumansInfant, NewbornPublic Healthcoxsackieenterovirusmyocarditisneonatal infection

Identifiers

PMID37768558
PMCPMC10540513
OpenAlexW4387116026

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.