Evidence map›Paper›PMID 37768531›Full record

ArticleDrug delivery and translational research2024

Metal-polyphenol microgels for oral delivery of puerarin to alleviate the onset of diabetes.

Si-Hui Li, Yan-Fei Li, Di Wu, Yu Xu, Hui-Jia Yan, Jiang-Ning Hu

Abstract read
PubMed Publisher
In one paragraph

Article in Drug delivery and translational research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Si-Hui LiResearch Group of Nutrition and Health, National Engineering Research Center of Seafood, Dalian Polytechnic University, Dalian, 116034, China.
Yan-Fei LiResearch Group of Nutrition and Health, National Engineering Research Center of Seafood, Dalian Polytechnic University, Dalian, 116034, China.
Di WuResearch Group of Nutrition and Health, National Engineering Research Center of Seafood, Dalian Polytechnic University, Dalian, 116034, China.
Yu XuResearch Group of Nutrition and Health, National Engineering Research Center of Seafood, Dalian Polytechnic University, Dalian, 116034, China.
Hui-Jia YanResearch Group of Nutrition and Health, National Engineering Research Center of Seafood, Dalian Polytechnic University, Dalian, 116034, China.
Jiang-Ning HuResearch Group of Nutrition and Health, National Engineering Research Center of Seafood, Dalian Polytechnic University, Dalian, 116034, China. hujiangning2005@hotmail.com.
Dalian Polytechnic University · CN

Funding

Central Funds Guiding the Local Science and Technology Development of China 2020JH6/10500002National Nature Science Foundation of China 32172208
6 · The paper itself

Abstract

Puerarin (Pue) is a naturally bioactive compound with many potential functions in regulating blood glucose and lipid metabolism. However, the low bioavailability and rapid elimination in vivo limit the application of Pue in diabetic treatment. Here, we developed a metal-polyphenol-functionalized microgel to effectively deliver Pue in vivo and eventually alleviate the onset of diabetes. Pue was initially encapsulated in alginate beads through electrospray technology, and further immersed in Fe

Indexed as

Diabetes Mellitus, ExperimentalIsoflavonesMicrogelsAnimalsMicePolyphenolsRatsRats, Sprague-DawleyIsoflavonesMicrogelsPolyphenolspuerarintannic acidCore–shell microgelsPuerarinSlow releaseType 2 diabetes mellitus

Identifiers

PMID37768531
OpenAlexW4387115695

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.