Evidence map›Paper›PMID 37768449›Full record

ArticleBulletin of experimental biology and medicine2023

Effective Connectivity of the Bilateral Amygdala, Dorsomedial Prefrontal, and Subgenual Anterior Cingulate Cortices: Feasibility of Positive Social Emotion Regulation Models for Real-Time Functional Magnetic Resonance Imaging.

D D Bezmaternykh, M E Mel'nikov, E D Petrovskii, K G Mazhirina, A A Savelov, K V Kalgin, M B Shtark, Y A Koush

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Article in Bulletin of experimental biology and medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

D D BezmaternykhResearch Institute of Molecular Biology and Biophysics, Federal Research Center of Fundamental and Translational Medicine, Novosibirsk, Russia.
M E Mel'nikovResearch Institute of Molecular Biology and Biophysics, Federal Research Center of Fundamental and Translational Medicine, Novosibirsk, Russia.
E D PetrovskiiInternational Tomography Center, Siberian Division of the Russian Academy of Sciences, Novosibirsk, Russia.
K G MazhirinaResearch Institute of Molecular Biology and Biophysics, Federal Research Center of Fundamental and Translational Medicine, Novosibirsk, Russia.
A A SavelovInternational Tomography Center, Siberian Division of the Russian Academy of Sciences, Novosibirsk, Russia.
K V KalginResearch Institute of Molecular Biology and Biophysics, Federal Research Center of Fundamental and Translational Medicine, Novosibirsk, Russia.
M B ShtarkResearch Institute of Molecular Biology and Biophysics, Federal Research Center of Fundamental and Translational Medicine, Novosibirsk, Russia.
Y A KoushDepartment of Biomedical Engineering, Yale University, New Haven, Connecticut, USA. yurykoush@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Effective connectivity based on functional magnetic resonance imaging (fMRI) allows assessing directions of interaction between brain regions. For real-time fMRI, we compared models of positive social emotion regulation based on a network involving the bilateral amygdala, dorsomedial prefrontal, and subgenual anterior cingulate cortex. The top-down regulation model implied modulation of the dorsomedial prefrontal cortex exerted onto other regions, while the bottom-up model implied the inverse modulation. The validity of model calculations was tested using the data from three healthy volunteers who imagined positive interactions with people in presented photos (stimuli). We confirmed the dominance of the top-down model and evaluated the number and duration of iterations required for model estimations. The study shows the applicability of the four-node effective connectivity models for regulation of positive social emotions using real-time fMRI, e.g., for neurofeedback applications.

Indexed as

AmygdalaEmotional RegulationEmotionsGyrus CinguliPrefrontal CortexAdultBrain MappingFemaleHumansMagnetic Resonance ImagingMaleNerve NetYoung Adultdynamic causal modelingeffective connectivitypositive social emotion regulationreal-time functional MRI

Identifiers

PMID37768449

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.