Evidence map›Paper›PMID 37768381›Full record

ArticleSports medicine - open2023

Effect of Tai Chi on Young Adults with Subthreshold Depression via a Stress-Reward Complex: A Randomized Controlled Trial.

Jingsong Wu, Jian Song, Youze He, Zhaoying Li, Haiyin Deng, Zhenming Huang, Xiaoting Xie, Nichol M L Wong, Jing Tao, Tatia M C Lee and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Sports medicine - open, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 7 pooled it
4.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 7 syntheses or guidelines pooled it, 15 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Jingsong Wu *College of Rehabilitation Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, People's Republic of China.
Jian Song *College of Rehabilitation Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, People's Republic of China.
Youze He *College of Rehabilitation Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, People's Republic of China.
Zhaoying LiCollege of Rehabilitation Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, People's Republic of China.
Haiyin DengCollege of Rehabilitation Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, People's Republic of China.
Zhenming HuangCollege of Rehabilitation Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, People's Republic of China.
Xiaoting XieCollege of Rehabilitation Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, People's Republic of China.
Nichol M L WongState Key Laboratory of Brain and Cognitive Sciences, The University of Hong Kong, Rm 656, The Jockey Club Tower, Pokfulam Road, Pokfulam, Hong Kong, People's Republic of China.
Jing TaoNational-Local Joint Engineering Research Center of Rehabilitation Medicine Technology, Fujian University of Traditional Chinese Medicine, Fuzhou, People's Republic of China. taojing01@fjtcm.edu.cn.
Tatia M C LeeState Key Laboratory of Brain and Cognitive Sciences, The University of Hong Kong, Rm 656, The Jockey Club Tower, Pokfulam Road, Pokfulam, Hong Kong, People's Republic of China. tmclee@hku.hk.
Chetwyn C H ChanDepartment of Psychology, The Education University of Hong Kong, Tai Po, Hong Kong, People's Republic of China. cchchan@eduhk.hk.
Fujian University of Traditional Chinese Medicine · CNHong Kong Jockey Club · CNEducation University of Hong Kong · HK

Funding

2022 Major Scientific and Technological Innovation Project of Fujian University of Traditional Chinese Medicine XJB20220062022 Research Project of Chinese Association of Rehabilitation Medicine KFKT-2022-013Key-Area Research and Development Program of Guangdong Province 2018B30334001National Natural Science Foundation of China 81804164
6 · The paper itself

Abstract

backgroundSubthreshold depression is a highly prevalent mood disorder in young adults. Mind-body exercises, such as Tai Chi, have been adopted as interventions for clinical depressive symptoms. However, the possible effect and underlying mechanism of Tai Chi on subthreshold depression of young individuals remain unclear. This randomized controlled study aimed to evaluate the effects of Tai Chi training and tested the combined stress and reward circuitry model for subthreshold depression.

resultsA total of 103 participants completed this trial, with 49 in the 12-week 24-style Tai Chi group and 54 participants in control group. Our results showed significantly lower scores on depressive symptoms (P = 0.002) and anxiety symptoms (P = 0.009) and higher scores on quality of life (P = 0.002) after Tai Chi training. There were significant reductions in salivary cortisol levels (P = 0.007) and putamen gray matter volume (P < 0.001) in the Tai Chi group. The changes in cortisol levels and putamen gray matter volume had direct (bootstrapping confidence interval [- 0.91, - 0.11]) and indirect effects (bootstrapping confidence interval [- 0.65, - 0.19]) on the changes induced by Tai Chi training on depressive symptoms, respectively.

conclusionThe stress-reward complex results indicated an interaction between lowering stress levels and increasing reward circuitry activity associated with the alleviation of depressive symptoms among participants. The 12-week Tai Chi training was effective in improving the symptoms and quality of life of young adults with subthreshold depression. Trial Registration Chinese Registry of Clinical Trials (Registration Number: ChiCTR1900028289, Registered December 12, 2019).

Indexed as

Gray matter volumeRandomized controlled trialSalivary cortisol levelSubthreshold depressionTai Chi training

Identifiers

PMID37768381
PMCPMC10539242
OpenAlexW4387114754

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.