Evidence map›Paper›PMID 37768371›Full record

ArticleEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2024

Serum levels of heavy metals in patients with Bell's palsy: a case-control study.

Nazim Bozan, Ömer Faruk Koçak, Canser Yılmaz Demir, Koray Avcı, Ömer Erdağ, Mahfuz Turan, Halit Demir

Abstract read
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In one paragraph

Article in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Heavy metal levels in malignant salivary gland tumours: a case-control study.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Nazim BozanDepartment of Otorhinolaryngology, Medical Faculty, Van Yüzüncü Yıl University, Van, 65090, Turkey. drnzmbozan@hotmail.com.ORCID http://orcid.org/0000-0002-2171-3830
Ömer Faruk KoçakDepartment of Plastic, Reconstructive and Aesthetic Surgery, Medical Faculty, Van Yüzüncü Yıl University, Van, Turkey.
Canser Yılmaz DemirDepartment of Plastic, Reconstructive and Aesthetic Surgery, Medical Faculty, Van Yüzüncü Yıl University, Van, Turkey.
Koray AvcıDepartment of Otorhinolaryngology, Medical Faculty, Van Yüzüncü Yıl University, Van, 65090, Turkey.
Ömer ErdağDepartment of Otorhinolaryngology, Medical Faculty, Van Yüzüncü Yıl University, Van, 65090, Turkey.
Mahfuz TuranDepartment of Otorhinolaryngology, Medical Faculty, Van Yüzüncü Yıl University, Van, 65090, Turkey.
Halit DemirDepartment of Chemistry, Faculty of Science, Van Yüzüncü Yıl University, Van, Turkey.
Van Yüzüncü Yıl Üniversitesi · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe exact etiology of Bell's palsy (BP) remains unknown, while its potential etiopathology includes neuritis and inflammation-related demyelination as in optic neuritis. It has been reported that disruption of heavy metal homeostasis may be associated with the inflammatory process of optic neuritis; therefore, heavy metals may be involved in the pathogenesis of facial nerve neuritis. In this study, we aimed to investigate serum levels of heavy metals including essential elements [iron (Fe), zinc (Zn), copper (Cu), cobalt (Co), and manganese (Mn)], and nonessential elements [lead (Pb) and cadmium (Cd)] in patients with BP.

methodsThe study included 25 patients with BP and 31 healthy volunteers. For each participant, serum levels of essential and nonessential elements were measured using the atomic absorption spectrophotometer method.

resultsSerum levels of essential elements were significantly lower in the patient group compared to the control group (p < 0.001, for each). Serum levels of Pb increased in the patient group compared to the control group although no significant difference was achieved (p = 0.105). In contrast, serum Cd levels increased significantly in the patient group compared to the control group (p < 0.001).

conclusionOur findings suggest that decreased essential and increased nonessential elements may be associated with BP and thus, serum concentrations of these elements should be taken into account in BP. Studies are warranted to determine the role of these elements in treatment of BP.

Indexed as

Bell PalsyFacial ParalysisMetals, HeavyNeuritisOptic NeuritisCadmiumCase-Control StudiesHumansLeadCadmiumLeadMetals, HeavyBell’s palsyEssential elementsFacial nerve palsyHeavy metals

Identifiers

PMID37768371
OpenAlexW4387116267

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.