Evidence map›Paper›PMID 37768011›Full record

ArticleEMBO molecular medicine2023

Single cell RNA sequencing sheds light on infiltrating T cells in idiopathic inflammatory myopathies.

Momina Yazdani, Lukas Mach, Michela Noseda

Open access · goldAbstract readComment
In one paragraph

Article in EMBO molecular medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Momina YazdaniNational Heart and Lung Institute, Imperial College London, London, UK.ORCID 0000-0002-1776-8070
Lukas MachNational Heart and Lung Institute, Imperial College London, London, UK.ORCID 0000-0001-7824-4468
Michela NosedaNational Heart and Lung Institute, Imperial College London, London, UK.ORCID 0000-0002-9553-5029
Imperial College London · GB

Funding

British Heart Foundation FS/CRTF/23/24444British Heart Foundation FS/CRTF/23/24448British Heart Foundation SP/19/1/34461
6 · The paper itself

Abstract

Idiopathic inflammatory myopathies (IIM), also referred to as "myositis," are a group of heterogeneous autoimmune disorders characterised by muscle weakness, atrophy and progressive reduced mobility (Lundberg et al, 2021). IIM represent a significant health burden in adult populations, affecting individuals at a mean age of 50 with an estimated prevalence of 2.9-34 per 100,000 (Dobloug et al, 2015; Svensson et al, 2017). IIM encompass several subtypes including dermatomyositis, immune-mediated necrotising myopathy, inclusion-body myositis, antisynthetase syndrome and polymyositis, which are characterised by specific clinical features, histopathological findings and autoantibody status (Pinal-Fernandez et al, 2020).

Indexed as

Autoimmune DiseasesDermatomyositisMyositisMyositis, Inclusion BodyAdultHumansMiddle AgedSequence Analysis, RNAT-Lymphocytes

Identifiers

PMID37768011
PMCPMC10565633
OpenAlexW4387115832

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.