Evidence map›Paper›PMID 37767538›Full record

ArticleVaccine: X2023

Short-term safety of inactivated SARS-Cov-2 vaccines in Chinese patients with central nervous system inflammatory demyelinating diseases.

Daidi Zhao, Wenting Zhang, Xue Ma, Runze Zhao, Lingling Yao, Jiarui Lu, Xu Yan, Miao Bai, Guoxun Zhang, Hongzeng Li and 1 more

Open access · goldAbstract read
In one paragraph

Article in Vaccine: X, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Daidi ZhaoDepartment of Neurology, Tangdu Hospital, Air Force Medical University, Xi'an 710038, China.
Wenting ZhangXijing Hospital of Digestive Disease, Air Force Medical University, Xi'an, China.
Xue MaDepartment of Neurology, Tangdu Hospital, Air Force Medical University, Xi'an 710038, China.
Runze ZhaoDepartment of Ophthalmology, Xijing Hospital, Air Force Medical University, Xi'an, China.
Lingling YaoDepartment of Rehabilitation Medicine, The Third People's Hospital of Chengdu, Chengdu, China.
Jiarui LuDepartment of Neurology, Tangdu Hospital, Air Force Medical University, Xi'an 710038, China.
Xu YanDepartment of Neurology, Tangdu Hospital, Air Force Medical University, Xi'an 710038, China.
Miao BaiDepartment of Neurology, Tangdu Hospital, Air Force Medical University, Xi'an 710038, China.
Guoxun ZhangDepartment of Neurology, Yan'an University Medical College No. 3 Affiliated Hospital, Xianyang, China.
Hongzeng LiDepartment of Neurology, Tangdu Hospital, Air Force Medical University, Xi'an 710038, China.
Jun GuoDepartment of Neurology, Tangdu Hospital, Air Force Medical University, Xi'an 710038, China.
Air Force Medical University · CNXijing Hospital · CNThird People's Hospital of Chengdu · CNYan'an University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: This study aims to evaluate the short-term safety of inactivated severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines in Chinese patients with central nervous system inflammatory demyelinating diseases (CNS IDDs). Methods: A web-based survey was conducted among patients with CNS IDDs from April 15 to 19, 2022 in China. In total, 645 patients with CNS IDDs were identified, including 425 patients with multiple sclerosis (MS), 194 with neuromyelitis optica spectrum disorder (NMOSD), and 26 with other CNS IDDs. The questionnaire consisted of demographic data, clinical records, history of SARS-CoV-2 vaccination, and vaccination-related symptoms within one month after vaccination. The demographic data, clinical information, and relapse rates between vaccinated and non-vaccinated patients were compared. Results: Among 645 patients with CNS IDDs, 78 were vaccinated and 567 were non-vaccinated with the vaccination rate of 12.1 %. Compared to non-vaccinated group, a lower percentage of patients on DMDs therapy (41.0 % vs. 71.8 %, Conclusions: No increased risk of vaccination-associated relapses among Chinese patients with CNS IDDs indicated that inactivated SARS-CoV-2 vaccines appear to be safe for this population.

Indexed as

Central nervous system inflammatory demyelinating diseasesCoronavirus disease 2019Inactivated severe acute respiratory syndrome coronavirus 2 vaccinesRelapse rateSafety

Identifiers

PMID37767538
PMCPMC10520881
OpenAlexW4386879739

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.