Evidence map›Paper›PMID 37767440›Full record

ArticleJournal of family medicine and primary care2023

Inflammatory markers in geriatric anemia: A study from North India.

Malvika Shastri, Mrinalini Kotru, Alpana Raizada, Bhawna Mahajan, Rajat Jain, Meera Sikka

Open access · goldAbstract read
In one paragraph

Article in Journal of family medicine and primary care, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Evaluation of Erythroid Maturation Patterns in Unexplained anemia in the Elderly.Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion · 2025
    Article
  4. Erythropoietin levels in geriatric anemia.Journal of family medicine and primary care · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Malvika ShastriDepartment of Pathology, University College of Medical Sciences and Guru Teg Bahadur Hospital, New Delhi, Delhi, India.
Mrinalini KotruDepartment of Pathology, University College of Medical Sciences and Guru Teg Bahadur Hospital, New Delhi, Delhi, India.
Alpana RaizadaDepartment of Medicine, University College of Medical Sciences and Guru Teg Bahadur Hospital, New Delhi, Delhi, India.
Bhawna MahajanDepartment of Biochemistry, GB Pant Institute of Post Graduate Medical Education and Research, New Delhi, Delhi, India.
Rajat JainDepartment of Pathology, University College of Medical Sciences and Guru Teg Bahadur Hospital, New Delhi, Delhi, India.
Meera SikkaDepartment of Pathology, University College of Medical Sciences and Guru Teg Bahadur Hospital, New Delhi, Delhi, India.
Guru Teg Bahadur Hospital · INUniversity College of Medical Sciences · INInstitute of Post Graduate Medical Education and Research · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Inflammation has several effects in the geriatrics with reference to iron deficiency anemia (IDA), anemia of chronic disease (ACD), and unexplained anemia (UA). Whether hyperinflammation is part of their pathogenesis or just incidental is unknown. Data are limited regarding inflammatory patterns in IDA, ACD, and UA in anemic geriatrics and inflammation as a component of UA. There is little known about the overlap of inflammation between ACD and UA. Objective: The study was undertaken to find the proportion of anemic geriatric patients, aged ≥60 years with raised serum levels of inflammatory markers and their study within IDA, ACD, and UA. Materials and Methods: Seventy-five anemic geriatric patients were evaluated for raised serum levels of inflammatory markers: high sensitive C-reactive protein (hsCRP), tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6), and interleukin-8 (IL-8) along with serum ferritin (SF). Results: Raised markers were seen in 94.7% of anemic geriatric patients.IL-8 was raised most frequently followed by TNF-α, IL-6, hsCRP, and SF. No distinct inflammatory profile could be elicited between ACD and UA. The hyperinflammatory profile irrespective of the underlying etiology of geriatric anemia suggests that aging Conclusion: Geriatric anemia can be thought to develop on background of subclinical low-grade inflammation along with superimposed nutritional deficiencies or chronic diseases.

Indexed as

Geriatric anemiahsCRPIL-6IL-8inflammatory markersTNF-α

Identifiers

PMID37767440
PMCPMC10521830
OpenAlexW4386226908

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.