Evidence map›Paper›PMID 37767333›Full record

ArticleBeilstein journal of organic chemistry2023

α-(Aminomethyl)acrylates as acceptors in radical-polar crossover 1,4-additions of dialkylzincs: insights into enolate formation and trapping.

Angel Palillero-Cisneros, Paola G Gordillo-Guerra, Fernando García-Alvarez, Olivier Jackowski, Franck Ferreira, Fabrice Chemla, Joel L Terán, Alejandro Perez-Luna

Abstract read
In one paragraph

Article in Beilstein journal of organic chemistry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Modern radical chemistry.Beilstein journal of organic chemistry · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Angel Palillero-CisnerosSorbonne Université, CNRS, Institut Parisien de Chimie Moléculaire, IPCM. 4 place Jussieu, 75005 Paris, France.
Paola G Gordillo-GuerraSorbonne Université, CNRS, Institut Parisien de Chimie Moléculaire, IPCM. 4 place Jussieu, 75005 Paris, France.
Fernando García-AlvarezSorbonne Université, CNRS, Institut Parisien de Chimie Moléculaire, IPCM. 4 place Jussieu, 75005 Paris, France.ORCID https://orcid.org/0000-0002-4833-9420
Olivier JackowskiSorbonne Université, CNRS, Institut Parisien de Chimie Moléculaire, IPCM. 4 place Jussieu, 75005 Paris, France.ORCID https://orcid.org/0000-0001-9162-3294
Franck FerreiraSorbonne Université, CNRS, Institut Parisien de Chimie Moléculaire, IPCM. 4 place Jussieu, 75005 Paris, France.ORCID https://orcid.org/0000-0002-7571-1830
Fabrice ChemlaSorbonne Université, CNRS, Institut Parisien de Chimie Moléculaire, IPCM. 4 place Jussieu, 75005 Paris, France.
Joel L TeránBenemérita Universidad Autonóma de Puebla, Instituto de Ciencias, ICUAP, Edificio IC-9, Complejo de Ciencias, C.U., 72570, Puebla, México.ORCID https://orcid.org/0000-0002-4055-4353
Alejandro Perez-LunaSorbonne Université, CNRS, Institut Parisien de Chimie Moléculaire, IPCM. 4 place Jussieu, 75005 Paris, France.ORCID https://orcid.org/0000-0002-5578-9024

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We demonstrate that α-(aminomethyl)acrylates are suitable acceptors for 1,4-additions of dialkylzincs in aerobic conditions. The air-promoted radical-polar crossover process involves the 1,4-addition of an alkyl radical followed by homolytic substitution at the zinc atom of dialkylzinc. Coordination of the nitrogen atom to zinc enables this S

Indexed as

radical–polar crossovertandem reactionstert-butanesulfinamidezinc radical transferβ-amino acids

Identifiers

PMID37767333
PMCPMC10520473

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.