Evidence map›Paper›PMID 37766910›Full record

ArticleCase reports in obstetrics and gynecology2023

The sFlt-1/PlGF Ratio Trend Is Useful in Predicting Preeclampsia Severity in Hyperreactio Luteinalis Complicated with Preeclampsia.

Risa Miyatake, Tatsuya Fujii, Keiichi Kumasawa, Mari Ichinose, Masatake Toshimitsu, Seisuke Sayama, Takahiro Seyama, Takayuki Iriyama, Takeshi Nagamatsu, Yutaka Osuga

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PubMed Full text at PMC Publisher
In one paragraph

Article in Case reports in obstetrics and gynecology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Risa MiyatakeDepartment of Obstetrics and Gynecology, Faculty of Medicine, The University of Tokyo, 113-8655, Japan.ORCID https://orcid.org/0000-0002-6330-2861
Tatsuya FujiiDepartment of Obstetrics and Gynecology, Faculty of Medicine, The University of Tokyo, 113-8655, Japan.ORCID https://orcid.org/0000-0003-0413-1238
Keiichi KumasawaDepartment of Obstetrics and Gynecology, Faculty of Medicine, The University of Tokyo, 113-8655, Japan.ORCID https://orcid.org/0000-0003-0865-604X
Mari IchinoseDepartment of Obstetrics and Gynecology, Faculty of Medicine, The University of Tokyo, 113-8655, Japan.ORCID https://orcid.org/0000-0002-2974-9109
Masatake ToshimitsuDepartment of Obstetrics and Gynecology, Faculty of Medicine, The University of Tokyo, 113-8655, Japan.ORCID https://orcid.org/0000-0002-0509-7812
Seisuke SayamaDepartment of Obstetrics and Gynecology, Faculty of Medicine, The University of Tokyo, 113-8655, Japan.ORCID https://orcid.org/0000-0003-0244-6332
Takahiro SeyamaDepartment of Obstetrics and Gynecology, Faculty of Medicine, The University of Tokyo, 113-8655, Japan.ORCID https://orcid.org/0000-0002-3030-4713
Takayuki IriyamaDepartment of Obstetrics and Gynecology, Faculty of Medicine, The University of Tokyo, 113-8655, Japan.ORCID https://orcid.org/0000-0001-7970-6695
Takeshi NagamatsuDepartment of Obstetrics and Gynecology, Faculty of Medicine, The University of Tokyo, 113-8655, Japan.ORCID https://orcid.org/0000-0003-1480-5785
Yutaka OsugaDepartment of Obstetrics and Gynecology, Faculty of Medicine, The University of Tokyo, 113-8655, Japan.ORCID https://orcid.org/0000-0002-6660-1066
The University of Tokyo · JPNational Center For Child Health and Development · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hyperreactio luteinalis (HL) is a rare condition that presents as bilateral ovarian enlargement during pregnancy. Typically, it is thought to be caused by increased production of human chorionic gonadotropin (hCG) associated with gestational trophoblastic diseases or multiple pregnancies. The prognosis is relatively good, with many cases resulting in term birth. However, some obstetric complications, such as preeclampsia (PE) and preterm births, have been reported. We present a serious case of HL with subsequent PE that resulted in preterm delivery at 31 weeks of gestation. The soluble fms-like tyrosine kinase-1 (sFlt-1)/placental growth factor (PlGF) ratio was very high at the onset of PE at 24 weeks of gestation, followed by a modest decline, which then increased in proportion to the exacerbation of symptoms. Since HL cases have also been reported to be associated with PE, repeated measurement of the sFlt-1/PlGF ratio proved useful for better pregnancy management.

Identifiers

PMID37766910
PMCPMC10522418
OpenAlexW4386857929

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.