Evidence map›Paper›PMID 37766559›Full record

ArticleFukushima journal of medical science2023

Cytokine profiles in an extremely preterm infant with congenital syphilis.

Eisuke Fukama, Tomoaki Nomura, Daisuke Hatanaka, Michiko Kusakari, Hidehiro Takahashi, Toshihiko Nakamura, Naoto Takahashi

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Fukushima journal of medical science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Eisuke FukamaDepartment of Neonatology, Japanese Red Cross Musashino Hospital.
Tomoaki NomuraDepartment of Neonatology, Japanese Red Cross Musashino Hospital.
Daisuke HatanakaDepartment of Neonatology, Japanese Red Cross Musashino Hospital.
Michiko KusakariDepartment of Neonatology, Japanese Red Cross Musashino Hospital.
Hidehiro TakahashiDepartment of Neonatology, Japanese Red Cross Musashino Hospital.
Toshihiko NakamuraDepartment of Neonatology, Japanese Red Cross Musashino Hospital.
Naoto TakahashiDepartment of Pediatrics, Tokyo University School of Medicine.
Musashino Red Cross Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report the cytokine profiles of an infant with congenital syphilis as a first case. This female infant was born by vaginal delivery at a gestational age of 27 weeks during her mother's treatment for syphilis. Elevation of T helper (Th)-1 cytokines (interleukin (IL)-2, IL-12) and IL-17, which supports immunological mechanisms of Th-1, was similar to that in cases of syphilis in adults. IL-6 and granulocyte colony-stimulating factor (G-CSF), the synergistic effects of which cause the leukemoid reaction, were also elevated. The levels of interferon-γ and IL-17 in cerebral spinal fluid, which are elevated in neurosyphilis in adults, were slightly elevated.

Indexed as

SyphilisSyphilis, CongenitalAdultCytokinesFemaleHumansInfantInfant, Extremely PrematureInfant, NewbornInterleukin-17CytokinesInterleukin-17congenital syphiliscytokineIL-12IL-17IL-2

Identifiers

PMID37766559
PMCPMC10694514
OpenAlexW4387082754

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.