Evidence map›Paper›PMID 37766540›Full record

ArticlemAbs

A library approach for the

Paul Arras, Han Byul Yoo, Lukas Pekar, Christian Schröter, Thomas Clarke, Simon Krah, Daniel Klewinghaus, Vanessa Siegmund, Andreas Evers, Stefan Zielonka

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in mAbs. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 1 institution in 2 countries.

Paul ArrasAntibody Discovery & Protein Engineering, Merck Healthcare KGaA, Darmstadt, Germany.
Han Byul YooAntibody Discovery & Protein Engineering, Merck Healthcare KGaA, Darmstadt, Germany.
Lukas PekarAntibody Discovery & Protein Engineering, Merck Healthcare KGaA, Darmstadt, Germany.
Christian SchröterADCs & Targeted NBE Therapeutics, Merck KGaA, Darmstadt, Germany.
Thomas ClarkeBioinformatics, EMD Serono, Billerica, MA, USA.
Simon KrahAntibody Discovery & Protein Engineering, Merck Healthcare KGaA, Darmstadt, Germany.
Daniel KlewinghausEarly Protein Supply & Characterization, Merck Healthcare KGaA, Darmstadt, Germany.
Vanessa SiegmundEarly Protein Supply & Characterization, Merck Healthcare KGaA, Darmstadt, Germany.
Andreas EversAntibody Discovery & Protein Engineering, Merck Healthcare KGaA, Darmstadt, Germany.
Stefan ZielonkaAntibody Discovery & Protein Engineering, Merck Healthcare KGaA, Darmstadt, Germany.ORCID 0000-0002-4649-2843
Merck (Germany) · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study, we generated a novel library approach for high throughput

Indexed as

Single-Domain AntibodiesAntigensComplementarity Determining RegionsGene LibraryHumansImmunizationAntigensComplementarity Determining RegionsSingle-Domain AntibodiesAntibody displayantibody engineeringhumanizationin silico developabilitylibrary designNGSsingle domain antibodyVHHyeast surface display

Identifiers

PMID37766540
PMCPMC10540653
OpenAlexW4387115934

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.