Evidence map›Paper›PMID 37766501›Full record

ArticleThe British journal of surgery2023

Long-term patient-reported outcomes of immediate breast reconstruction after mastectomy for breast cancer: population-based cohort study.

Leigh Johnson, Paul White, Ranjeet Jeevan, John Browne, Carmel Gulliver-Clarke, Joe O'Donoghue, Syed Mohiuddin, William Hollingworth, Patricia Fairbrother, Mairead MacKenzie and 2 more

Open access · hybridAbstract read
In one paragraph

Article in The British journal of surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
6.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 8 institutions in 2 countries.

Leigh JohnsonTranslational Health Sciences, Bristol Medical School, Bristol, UK.
Paul WhiteApplied Statistics Group, University of the West of England, Bristol, UK.
Ranjeet JeevanDepartment of Plastic Surgery, Manchester University NHS Foundation Trust, Manchester, UK.
John BrowneSchool of Public Health, University College Cork, Cork, Ireland.
Carmel Gulliver-ClarkeDepartment of Breast Surgery, Western Sussex Hospitals NHS Foundation Trust, Worthing, UK.
Joe O'DonoghueDepartment of Plastic Surgery, Royal Victoria Infirmary, Newcastle upon Tyne NHS Foundation Trust, Newcastle upon Tyne, UK.
Syed MohiuddinTranslational Health Sciences, Bristol Medical School, Bristol, UK.
William HollingworthTranslational Health Sciences, Bristol Medical School, Bristol, UK.ORCID 0000-0002-0840-6254
Patricia FairbrotherIndependent Cancer Patients Voice (ICPV), UK.
Mairead MacKenzieIndependent Cancer Patients Voice (ICPV), UK.
Chris HolcombeLinda McCartney Centre, Royal Liverpool and Broadgreen University Hospital, Liverpool, UK.
Shelley PotterTranslational Health Sciences, Bristol Medical School, Bristol, UK.ORCID 0000-0002-6977-312X
The Patients Association · GBManchester University NHS Foundation Trust · GBRoyal Liverpool and Broadgreen University Hospital NHS Trust · GBRoyal Victoria Infirmary · GBSouthmead Hospital · GBUniversity College Cork · IEUniversity of the West of England · GBWorthing Hospital · GB

Funding

Department of Health
6 · The paper itself

Abstract

backgroundBreast reconstruction is offered to improve quality of life for women after mastectomy for breast cancer, but information regarding the long-term patient-reported outcomes of different reconstruction procedures is currently lacking. The Brighter study aimed to evaluate long-term patient-reported outcomes after immediate breast reconstruction (IBR) in a population-based cohort.

methodsWomen who underwent mastectomy with IBR for breast cancer in England between 1 January 2008 and 31 March 2009 were identified from National Health Service Hospital Episode Statistics. Surviving women were invited to complete the BREAST-Q, EQ-5D-5L™, and ICECAP-A at least 12 years after the index procedure. Questionnaires were scored according to developers' instructions and compared by IBR type.

resultsSome 1236 women underwent IBR; 343 (27.8 per cent) had 2-stage expander/implant, 630 (51.0 per cent) latissimus dorsi, and 263 (21.3 per cent) abdominal flap reconstructions, with a mean(s.d.) follow-up of 13.3(0.5) years. Women who underwent abdominal flap reconstruction reported higher scores in all BREAST-Q domains than those who had other procedures. These differences remained statistically significant and clinically meaningful after adjusting for age, ethnicity, geographical region, socioeconomic status, smoking, BMI, and complications. The greatest difference was seen in scores for satisfaction with breasts; women who had abdominal flap reconstructions reported scores that were 13.17 (95 per cent c.i. 9.48 to 16.87) points; P < 0.001) higher than those among women who had two-stage expander/implant procedures. Women who underwent latissimus dorsi reconstruction reported significantly more pain/discomfort on the EQ-5D-5L™, but no other differences between procedures were seen.

conclusionLong-term patient-reported outcomes are significantly better following abdominal flap reconstruction than other traditional procedure types. These findings should be shared with women considering IBR to help them make informed decisions about their surgical options.

Indexed as

Breast NeoplasmsMammaplastyCohort StudiesFemaleHumansMastectomyQuality of LifeRetrospective StudiesState MedicineTreatment Outcome

Identifiers

PMID37766501
PMCPMC10638530
OpenAlexW4387115443

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.