Evidence map›Paper›PMID 37766350›Full record

ArticleViruses2023

Enhanced IL-17 Producing and Maintained Cytolytic Effector Functions of Gut Mucosal CD161

Siva Thirugnanam, Edith M Walker, Faith Schiro, Pyone P Aye, Jay Rappaport, Namita Rout

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 64% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Siva ThirugnanamTulane National Primate Research Center, Covington, LA 70433, USA.
Edith M WalkerTulane National Primate Research Center, Covington, LA 70433, USA.
Faith SchiroTulane National Primate Research Center, Covington, LA 70433, USA.
Pyone P AyeTulane National Primate Research Center, Covington, LA 70433, USA.
Jay RappaportTulane National Primate Research Center, Covington, LA 70433, USA.
Namita RoutTulane National Primate Research Center, Covington, LA 70433, USA.
Tulane University · US

Funding

Tulane NPRC SPF Sheltered Outdoor Enclosure ExpansionP51OD011104 · OD · TULANE UNIVERSITY OF LOUISIANA · PI L Lee HAMM · 2012 to 2026
$142.4M
Viral Testing CoreU42OD024282 · OD · TULANE UNIVERSITY OF LOUISIANA · PI KASI E RUSSELL-LODRIGUE · 2017 to 2026
$25.7M
Viral Testing Core - Maintenance of an SPF Macaque Breeding Colony for AIDS ResearchU42OD010568 · OD · TULANE UNIVERSITY OF LOUISIANA · PI Eric J. Vallender · 2013 to 2026
$21.7M
Gamma Delta T cell and microbial modulation to target chronic SIV-associated inflammationR01DK131930 · NIDDK · TULANE UNIVERSITY OF LOUISIANA · PI Namita Rout · 2022 to 2026
$3.6M
Genetically Modified Gamma Delta T Cells to Target SIV ReservoirsR33AI136100 · NIAID · TULANE UNIVERSITY OF LOUISIANA · PI ROUT, NAMITA · 2020 to 2022
$1.5M
High Throughput Multicolor Flow Cytometer Cell AnalyzerS10OD026800 · OD · TULANE UNIVERSITY OF LOUISIANA · PI KAUR, AMITINDER · 2019 to 2019
$594k
Innate immune mechanisms of epithelial barrier disruption during treated HIV and SIV infectionsR56DK131531 · NIDDK · TULANE UNIVERSITY OF LOUISIANA · PI ROUT, NAMITA, WELSH, DAVID A · 2022 to 2022
$555k
Development of Gamma delta CAR-T cells to target CNS HIV reservoirR21MH132483 · NIMH · TULANE UNIVERSITY OF LOUISIANA · PI ROUT, NAMITA · 2023 to 2024
$507k
NIAID NIH HHS R33 AI136100NIDDK NIH HHS R01 DK131930NIDDK NIH HHS R01DK131930NIDDK NIH HHS R56 DK131531NIDDK NIH HHS R56DK131531NIH HHS P51 OD011104NIH HHS S10 OD026800NIH HHS U42 OD010568NIH HHS U42 OD024282NIMH NIH HHS R21 MH132483NIMH NIH HHS R21MH132483
6 · The paper itself

Abstract

Previous studies have indicated that the loss of CD161-expressing CD4

Indexed as

HIV InfectionsSimian Acquired Immunodeficiency SyndromeSimian Immunodeficiency VirusAnimalsCD8-Positive T-LymphocytesHumansInterleukin-17Intestinal MucosaMacaca mulattaInterleukin-17CD161IL-17mucosal immunitySIVT cellsTNF-α

Identifiers

PMID37766350
PMCPMC10535321
OpenAlexW4386836138

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.