Evidence map›Paper›PMID 37766330›Full record

ArticleViruses2023

Genomic Epidemiology and Lineage Dynamics of SARS-CoV-2 in Bulgaria: Insights from a Three-Year Pandemic Analysis.

Marta Giovanetti, Eleonora Cella, Ivan Ivanov, Lyubomira Grigorova, Ivan Stoikov, Deyan Donchev, Reneta Dimitrova, Svetoslav Nanev Slavov, Carla Mavian, Vagner Fonseca and 9 more

Abstract read
In one paragraph

Article in Viruses, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Marta GiovanettiInstituto Rene Rachou Fundação Oswaldo Cruz, Belo Horizonte 30190-009, Brazil.ORCID 0000-0002-5849-7326
Eleonora CellaBurnett School of Biomedical Sciences, University of Central Florida, Orlando, FL 32816, USA.ORCID 0000-0002-7870-9744
Ivan IvanovNational Center of Infectious and Parasitic Diseases, 1504 Sofia, Bulgaria.ORCID 0000-0002-2616-894X
Lyubomira GrigorovaNational Center of Infectious and Parasitic Diseases, 1504 Sofia, Bulgaria.
Ivan StoikovNational Center of Infectious and Parasitic Diseases, 1504 Sofia, Bulgaria.ORCID 0000-0002-9924-8553
Deyan DonchevNational Center of Infectious and Parasitic Diseases, 1504 Sofia, Bulgaria.ORCID 0000-0001-7447-7627
Reneta DimitrovaNational Center of Infectious and Parasitic Diseases, 1504 Sofia, Bulgaria.ORCID 0000-0001-7711-6798
Svetoslav Nanev SlavovButantan Institute, São Paulo 05508-040, Brazil.ORCID 0000-0003-0805-6140
Carla MavianEmerging Pathogens Institute, Department of Pathology, Immunology and Laboratory Medicine, College of Medicine, University of Florida, Gainesville, FL 32610, USA.ORCID 0000-0003-3819-5520
Vagner FonsecaDepartment of Exact and Earth Sciences, University of the State of Bahia, Salvador 40285-001, Brazil.ORCID 0000-0001-5521-6448
Fabio ScarpaDepartment of Biomedical Sciences, University of Sassari, 07100 Sassari, Italy.ORCID 0000-0002-3501-714X
Alessandra BorsettiNational HIV/AIDS Research Center (CNAIDS), National Institute of Health, 00118 Rome, Italy.ORCID 0000-0002-5401-135X
Neli KorsunNational Center of Infectious and Parasitic Diseases, 1504 Sofia, Bulgaria.ORCID 0000-0002-3188-2283
Ivelina TrifonovaNational Center of Infectious and Parasitic Diseases, 1504 Sofia, Bulgaria.ORCID 0000-0002-4543-6831
Veselin DobrinovNational Center of Infectious and Parasitic Diseases, 1504 Sofia, Bulgaria.
Todor KantardjievNational Center of Infectious and Parasitic Diseases, 1504 Sofia, Bulgaria.
Iva ChristovaNational Center of Infectious and Parasitic Diseases, 1504 Sofia, Bulgaria.
Massimo CiccozziUnit of Medical Statistics and Molecular Epidemiology, Universita Campus Bio-Medico di Roma, 00128 Rome, Italy.ORCID 0000-0003-3866-9239
Ivailo AlexievNational Center of Infectious and Parasitic Diseases, 1504 Sofia, Bulgaria.ORCID 0000-0002-3186-1124

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The COVID-19 pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has brought about significant challenges worldwide. In this study, we present a comprehensive analysis of the genomic epidemiology and lineage dynamics of SARS-CoV-2 in Bulgaria over a three-year period. Through extensive genomic sequencing and data analysis, we investigated the evolution of the virus, the emergence of variants of concern (VOCs), and their impact on the country's pandemic trajectory. We also assessed the relationship between viral diversity and COVID-19 morbidity and mortality in Bulgaria. Our findings shed light on the temporal and spatial distribution of SARS-CoV-2 lineages and provide crucial insights into the dynamics of the pandemic in the country. The interplay between international travel and viral transmission plays a significant role in the emergence and dissemination of different SARS-CoV-2 variants. The observed proportions of exportation to various continents provide insights into the potential pathways through which these lineages spread globally. Understanding the genomic epidemiology of SARS-CoV-2 in Bulgaria is essential for formulating targeted public health strategies, enhancing vaccination efforts, and effectively managing future outbreaks.

Indexed as

COVID-19SARS-CoV-2BulgariaGenomicsHumansPandemicsBulgariaepidemiologygenomic surveillanceSARS-CoV-2viral evolution

Identifiers

PMID37766330
PMCPMC10536935

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.