Evidence map›Paper›PMID 37766297›Full record

ArticleViruses2023

Transmission Dynamics of Crimean-Congo Haemorrhagic Fever Virus (CCHFV): Evidence of Circulation in Humans, Livestock, and Rodents in Diverse Ecologies in Kenya.

Dorcus C A Omoga, David P Tchouassi, Marietjie Venter, Edwin O Ogola, Josephine Osalla, Anne Kopp, Inga Slothouwer, Baldwyn Torto, Sandra Junglen, Rosemary Sang

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 3 countries.

Dorcus C A OmogaInternational Centre of Insect Physiology and Ecology, Nairobi P.O. Box 30772-00100, Kenya.ORCID 0000-0003-1624-5283
David P TchouassiInternational Centre of Insect Physiology and Ecology, Nairobi P.O. Box 30772-00100, Kenya.ORCID 0000-0001-9910-4704
Marietjie VenterZoonotic Arbo and Respiratory Virus Research Program, Centre for Viral Zoonoses, Department of Medical Virology, Faculty of Health, University of Pretoria, Private Bag X 323, Gezina 0031, South Africa.ORCID 0000-0003-2696-824X
Edwin O OgolaInternational Centre of Insect Physiology and Ecology, Nairobi P.O. Box 30772-00100, Kenya.ORCID 0000-0002-4415-8366
Josephine OsallaInternational Centre of Insect Physiology and Ecology, Nairobi P.O. Box 30772-00100, Kenya.ORCID 0000-0003-2392-6984
Anne KoppInstitute of Virology, Charité Universitätsmedizin Berlin, Corporate Member of Free University Berlin, Humboldt-University Berlin, and Berlin Institute of Health, Chariteplatz 1, 10117 Berlin, Germany.
Inga SlothouwerInstitute of Virology, Charité Universitätsmedizin Berlin, Corporate Member of Free University Berlin, Humboldt-University Berlin, and Berlin Institute of Health, Chariteplatz 1, 10117 Berlin, Germany.ORCID 0000-0002-0809-5388
Baldwyn TortoInternational Centre of Insect Physiology and Ecology, Nairobi P.O. Box 30772-00100, Kenya.
Sandra JunglenInstitute of Virology, Charité Universitätsmedizin Berlin, Corporate Member of Free University Berlin, Humboldt-University Berlin, and Berlin Institute of Health, Chariteplatz 1, 10117 Berlin, Germany.
Rosemary SangInternational Centre of Insect Physiology and Ecology, Nairobi P.O. Box 30772-00100, Kenya.
International Centre of Insect Physiology and Ecology · KEBerlin Institute of Health at Charité - Universitätsmedizin Berlin · DEUniversity of Pretoria · ZA

Funding

Wellcome TrustWellcome Trust 222005/Z/20/Z
6 · The paper itself

Abstract

Crimean-Congo haemorrhagic fever virus (CCHFV) is the causative agent of CCHF, a fatal viral haemorrhagic fever disease in humans. The maintenance of CCHFV in the ecosystem remains poorly understood. Certain tick species are considered as vectors and reservoirs of the virus. Diverse animals are suspected as amplifiers, with only scarce knowledge regarding rodents in virus epidemiology. In this study, serum samples from febrile patients, asymptomatic livestock (cattle, donkeys, sheep, and goats), and peridomestic rodents from Baringo (Marigat) and Kajiado (Nguruman) counties within the Kenyan Rift Valley were screened for acute CCHFV infection by RT-PCR and for CCHFV exposure by ELISA. RT-PCR was performed on all livestock samples in pools (5-7/pool by species and site) and in humans and rodents individually. CCHFV seropositivity was significantly higher in livestock (11.9%, 113/951) compared to rodents (6.5%, 6/93) and humans (5.9%, 29/493) (

Indexed as

Hemorrhagic Fever, CrimeanHemorrhagic Fever Virus, Crimean-CongoAnimalsCattleEcosystemFeverGoatsHumansImmunoglobulin MKenyaLivestockNucleotidesPhylogenySheepImmunoglobulin MNucleotidesCrimean–Congo haemorrhagic feverfebrile patientsKenyalivestockperidomestic rodentsserological surveillance

Identifiers

PMID37766297
PMCPMC10535211
OpenAlexW4386526004

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.