Evidence map›Paper›PMID 37766292›Full record

ArticleViruses2023

Mannose-Binding Lectins as Potent Antivirals against SARS-CoV-2.

Victória Riquena Grosche, Leandro Peixoto Ferreira Souza, Giulia Magalhães Ferreira, Marco Guevara-Vega, Tamara Carvalho, Romério Rodrigues Dos Santos Silva, Karla Lilian Rodrigues Batista, Rodrigo Paolo Flores Abuna, João Santana Silva, Marília de Freitas Calmon and 6 more

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 13 citations in OpenAlex.

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  10. A Review of the Leishmanicidal Properties of Lectins.Current protein & peptide science · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 6 institutions in 1 country.

Victória Riquena GroscheLaboratory of Antiviral Research, Institute of Biomedical Science (ICBIM), Federal University of Uberlândia (UFU), Uberlândia 38405-317, Brazil.ORCID 0000-0001-7313-1261
Leandro Peixoto Ferreira SouzaInnovation Center in Salivary Diagnostic and Nanobiotechnology, Institute of Biomedical Science (ICBIM), Federal University of Uberlândia (UFU), Uberlândia 38405-317, Brazil.
Giulia Magalhães FerreiraLaboratory of Antiviral Research, Institute of Biomedical Science (ICBIM), Federal University of Uberlândia (UFU), Uberlândia 38405-317, Brazil.
Marco Guevara-VegaInnovation Center in Salivary Diagnostic and Nanobiotechnology, Institute of Biomedical Science (ICBIM), Federal University of Uberlândia (UFU), Uberlândia 38405-317, Brazil.
Tamara CarvalhoInstitute of Biosciences, Languages, and Exact Sciences (Ibilce), São Paulo State University (Unesp), São José do Rio Preto 15054-000, Brazil.
Romério Rodrigues Dos Santos SilvaCenter of Agrarian Science and Biodiversity, Federal University of Cariri (UFCA), Crato 63130-025, Brazil.ORCID 0000-0003-2712-4495
Karla Lilian Rodrigues BatistaLaboratory of Microbial Pathogenesis, CEUMA University, São Luís 65045-380, Brazil.
Rodrigo Paolo Flores AbunaDepartment of Biochemistry and Immunology, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto 14049-900, Brazil.
João Santana SilvaDepartment of Biochemistry and Immunology, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto 14049-900, Brazil.ORCID 0000-0002-3410-3927
Marília de Freitas CalmonInstitute of Biosciences, Languages, and Exact Sciences (Ibilce), São Paulo State University (Unesp), São José do Rio Preto 15054-000, Brazil.ORCID 0000-0001-5203-0103
Paula RahalInstitute of Biosciences, Languages, and Exact Sciences (Ibilce), São Paulo State University (Unesp), São José do Rio Preto 15054-000, Brazil.
Luis Cláudio Nascimento da SilvaLaboratory of Microbial Pathogenesis, CEUMA University, São Luís 65045-380, Brazil.ORCID 0000-0002-4206-0904
Bruno Silva AndradeLaboratory of Bioinformatics and Computational Chemistry, State University of Southwest of Bahia, Jequié 45205-490, Brazil.ORCID 0000-0002-8031-9454
Claudener Souza TeixeiraCenter of Agrarian Science and Biodiversity, Federal University of Cariri (UFCA), Crato 63130-025, Brazil.
Robinson Sabino-SilvaInnovation Center in Salivary Diagnostic and Nanobiotechnology, Institute of Biomedical Science (ICBIM), Federal University of Uberlândia (UFU), Uberlândia 38405-317, Brazil.ORCID 0000-0002-2104-5780
Ana Carolina Gomes JardimLaboratory of Antiviral Research, Institute of Biomedical Science (ICBIM), Federal University of Uberlândia (UFU), Uberlândia 38405-317, Brazil.ORCID 0000-0002-6348-7923
Universidade Federal de Uberlândia · BRUniversidade Estadual Paulista (Unesp) · BRUniversidade Ceuma · BRUniversidade de São Paulo · BRUniversidade Federal do Cariri · BRSouthwest Bahia State University · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The SARS-CoV-2 entry into host cells is mainly mediated by the interactions between the viral spike protein (S) and the ACE-2 cell receptor, which are highly glycosylated. Therefore, carbohydrate binding agents may represent potential candidates to abrogate virus infection. Here, we evaluated the in vitro anti-SARS-CoV-2 activity of two mannose-binding lectins isolated from the Brazilian plants

Indexed as

Antiviral AgentsCOVID-19HumansLectinsMannose-Binding LectinsMolecular Docking SimulationSARS-CoV-2Antiviral AgentsLectinsMannose-Binding LectinsantiviralsCOVID-19glycansmannose-biding lectinsnatural compoundsSARS-CoV-2

Identifiers

PMID37766292
PMCPMC10536204
OpenAlexW4386476091

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.