Evidence map›Paper›PMID 37766286›Full record

ArticleViruses2023

The Use of High-Flow Nasal Cannula and Non-Invasive Mechanical Ventilation in the Management of COVID-19 Patients: A Prospective Study.

Sumalatha Arunachala, Ashwaghosha Parthasarathi, Chetak Kadabasal Basavaraj, Sowmya Malamardi, Shreya Chandran, Hariharan Venkataraman, Mohammed Kaleem Ullah, Koustav Ganguly, Swapna Upadhyay, Padukudru Anand Mahesh

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 4 countries.

Sumalatha ArunachalaDepartment of Respiratory Medicine, JSS Medical College, JSS Academy of Higher Education and Research, Mysuru 570015, India.ORCID 0000-0001-5858-8298
Ashwaghosha ParthasarathiAllergy, Asthma, and Chest Centre, Krishnamurthy Puram, Mysuru 570004, India.ORCID 0000-0002-7270-0247
Chetak Kadabasal BasavarajDepartment of Respiratory Medicine, JSS Medical College, JSS Academy of Higher Education and Research, Mysuru 570015, India.ORCID 0000-0002-7422-8353
Sowmya MalamardiDepartment of Respiratory Medicine, JSS Medical College, JSS Academy of Higher Education and Research, Mysuru 570015, India.
Shreya ChandranDepartment of Respiratory Medicine, JSS Medical College, JSS Academy of Higher Education and Research, Mysuru 570015, India.
Hariharan VenkataramanDepartment of Respiratory Medicine, JSS Medical College, JSS Academy of Higher Education and Research, Mysuru 570015, India.
Mohammed Kaleem UllahCentre for Excellence in Molecular Biology and Regenerative Medicine (A DST-FIST Supported Center), Department of Biochemistry (A DST-FIST Supported Department), JSS Medical College, JSS Academy of Higher Education and Research, Mysuru 570015, India.ORCID 0000-0001-8470-3114
Koustav GangulyUnit of Integrative Toxicology, Institute of Environmental Medicine (IMM), Karolinska Institute, 17177 Stockholm, Sweden.ORCID 0000-0001-8531-8154
Swapna UpadhyayUnit of Integrative Toxicology, Institute of Environmental Medicine (IMM), Karolinska Institute, 17177 Stockholm, Sweden.ORCID 0000-0003-4699-4082
Padukudru Anand MaheshDepartment of Respiratory Medicine, JSS Medical College, JSS Academy of Higher Education and Research, Mysuru 570015, India.ORCID 0000-0003-1632-5945
JSS Academy of Higher Education and Research · INKarolinska Institutet · SERutgers, The State University of New Jersey · US

Funding

Research Training at the Confluence of Infectious and Non-Communicable Diseases in IndiaD43TW010332 · FIC · UNIVERSITY OF CALIFORNIA BERKELEY · PI COX, JEFFERY S · 2017 to 2022
$836k
FIC NIH HHS D43 TW010332
6 · The paper itself

Abstract

High-flow nasal cannula (HFNC) and ventilator-delivered non-invasive mechanical ventilation (NIV) were used to treat acute respiratory distress syndrome (ARDS) due to COVID-19 pneumonia, especially in low- and middle-income countries (LMICs), due to lack of ventilators and manpower resources despite the paucity of data regarding their efficacy. This prospective study aimed to analyse the efficacy of HFNC versus NIV in the management of COVID-19 ARDS. A total of 88 RT-PCR-confirmed COVID-19 patients with moderate ARDS were recruited. Linear regression and generalized estimating equations (GEEs) were used for trends in vital parameters over time. A total of 37 patients were on HFNC, and 51 were on NIV. Patients in the HFNC group stayed slightly but not significantly longer in the ICU as compared to their NIV counterparts (HFNC vs. NIV: 8.00 (4.0-12.0) days vs. 7.00 (2.0-12.0) days;

Indexed as

COVID-19Noninvasive VentilationRespiratory Distress SyndromeRespiratory InsufficiencyCannulaHumansProspective StudiesRespiration, ArtificialARDSCOVID-19high-flow nasal cannulanon-invasive mechanical ventilationpneumonia

Identifiers

PMID37766286
PMCPMC10535869
OpenAlexW4386444096

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.