Evidence map›Paper›PMID 37766255›Full record

ArticleViruses2023

Clinical Characterization of Respiratory Syncytial Virus Infection in Adults: A Neglected Disease?

Cassia F Estofolete, Cecília A Banho, Alice T Verro, Flora A Gandolfi, Bárbara F Dos Santos, Livia Sacchetto, Beatriz de C Marques, Nikos Vasilakis, Maurício L Nogueira

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Observational
  9. Severe respiratory syncytial virus disease.Journal of intensive medicine · 2024
    Review
  10. Journal of preventive medicine and hygiene · 2024
    Article
  11. Review
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Cassia F EstofoleteLaboratório de Pesquisas em Virologia, Faculdade de Medicina de São José do Rio Preto (FAMERP), São José do Rio Preto 15090-000, SP, Brazil.ORCID 0000-0001-7324-1591
Cecília A BanhoLaboratório de Pesquisas em Virologia, Faculdade de Medicina de São José do Rio Preto (FAMERP), São José do Rio Preto 15090-000, SP, Brazil.ORCID 0000-0001-5090-1534
Alice T VerroHospital de Base of São José do Rio Preto, São José do Rio Preto 15090-000, SP, Brazil.ORCID 0000-0003-0285-3640
Flora A GandolfiLaboratório de Pesquisas em Virologia, Faculdade de Medicina de São José do Rio Preto (FAMERP), São José do Rio Preto 15090-000, SP, Brazil.ORCID 0000-0001-9815-8479
Bárbara F Dos SantosLaboratório de Pesquisas em Virologia, Faculdade de Medicina de São José do Rio Preto (FAMERP), São José do Rio Preto 15090-000, SP, Brazil.
Livia SacchettoLaboratório de Pesquisas em Virologia, Faculdade de Medicina de São José do Rio Preto (FAMERP), São José do Rio Preto 15090-000, SP, Brazil.ORCID 0000-0001-9716-6899
Beatriz de C MarquesLaboratório de Pesquisas em Virologia, Faculdade de Medicina de São José do Rio Preto (FAMERP), São José do Rio Preto 15090-000, SP, Brazil.
Nikos VasilakisDepartment of Pathology, The University of Texas Medical Branch, Galveston, TX 77555, USA.ORCID 0000-0002-0708-3289
Maurício L NogueiraLaboratório de Pesquisas em Virologia, Faculdade de Medicina de São José do Rio Preto (FAMERP), São José do Rio Preto 15090-000, SP, Brazil.ORCID 0000-0003-1102-2419
Faculdade de Medicina de São José do Rio Preto · BRHospital de Base · BRThe University of Texas Medical Branch at Galveston · US

Funding

Coordinating Research on Emerging Arboviral Threats Encompassing the Neotropics II (CREATE-NEO II)U01AI151807 · NIAID · UNIVERSITY OF TEXAS MED BR GALVESTON · PI Kathryn Alyce Hanley, MAURICIO Lacerda NOGUEIRA · 2020 to 2026
$9.8M
NIAID NIH HHS U01 AI151807
6 · The paper itself

Abstract

Lower respiratory tract infections (LRIs) are a significant cause of disability-adjusted life-years (DALYs) across all age groups, especially in children under 9 years of age, and adults over 75. The main causative agents are viruses, such as influenza and respiratory syncytial virus (RSV). Viral LRIs in adults have historically received less attention. This study investigated the incidence of RSV and influenza in adult patients admitted to a referral hospital, as well as the clinical profile of these infections. Molecular testing was conducted on nasopharyngeal samples taken from a respiratory surveillance cohort comprising adult (15-59 years) and elderly (60+ years) hospitalized patients who tested negative for SARS-CoV-2, to determine the prevalence for influenza and RSV. Influenza was found to be less frequent among the elderly. The main symptoms of RSV infections were cough, fever, dyspnea, malaise, and respiratory distress, while headache, nasal congestion, a sore throat, and myalgia were most frequent in influenza. Elderly patients with RSV were not found to have more severe illness than adults under age 60, underscoring the importance of providing the same care to adults with this viral infection.

Indexed as

COVID-19Influenza, HumanRespiratory Syncytial Virus, HumanRespiratory Syncytial Virus InfectionsAdultAgedChildHumansMiddle AgedNeglected DiseasesSARS-CoV-2influenza A virusinfluenza B virusrespiratory syncytial virussevere acute respiratory syndrome

Identifiers

PMID37766255
PMCPMC10536488
OpenAlexW4386325548

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.