Evidence map›Paper›PMID 37766246›Full record

ArticleViruses2023

Effect of Different Levels of Maternally Derived Genotype VII Newcastle Disease Virus-Specific Hemagglutination Inhibition Antibodies on Protection against Virulent Challenge in Chicks.

Mei Liu, Xinyue Shen, Yan Yu, Jianmei Li, Jianhua Fan, Xuebo Jia, Yabin Dai

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Mei LiuJiangsu Institute of Poultry Sciences, Yangzhou 225125, China.
Xinyue ShenJiangsu Institute of Poultry Sciences, Yangzhou 225125, China.
Yan YuJiangsu Institute of Poultry Sciences, Yangzhou 225125, China.
Jianmei LiJiangsu Institute of Poultry Sciences, Yangzhou 225125, China.
Jianhua FanJiangsu Institute of Poultry Sciences, Yangzhou 225125, China.
Xuebo JiaJiangsu Institute of Poultry Sciences, Yangzhou 225125, China.
Yabin DaiJiangsu Institute of Poultry Sciences, Yangzhou 225125, China.
Poultry Research Institute · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Newcastle disease (ND), caused by the virulent Newcastle disease virus (NDV), is an acute, highly contagious, and economically significant avian disease worldwide. Vaccination is the most effective measure for controlling ND. In recent years, vaccines matched with the prevalent strains of genotype VII have been developed and are now commercially available. These vaccines can provide full protection for chickens against clinical disease and mortality after challenges with genotype VII viruses and significantly decrease virus shedding compared to conventional vaccines belonging to genotypes I and II. Vaccinated hens can transfer antibodies to their offspring through the egg yolk. Maternally derived antibodies can provide passive protection against diseases but can also interfere with vaccination efficacy early in life. This study was conducted on chicks hatched from hens vaccinated with a commercial genotype VII NDV-matched vaccine to investigate the correlation between hemagglutination inhibition (HI) antibody levels in chicks and hens and the decaying pattern of maternally derived HI antibodies, and to evaluate the protective efficacy of different levels of maternally derived HI antibodies against challenge with a virulent NDV strain of genotype VII based on survivability and virus shedding. The HI antibody titers in chicks at hatching were about 1.3 log

Indexed as

ChickensNewcastle DiseaseAnimalsAntibodies, ViralFemaleGenotypeHemagglutinationNewcastle disease virusAntibodies, Viralchickefficacygenotype VII-matched vaccinehemagglutination inhibition antibodymaternally derived antibodyNewcastle diseasesurvivabilityvirus shedding

Identifiers

PMID37766246
PMCPMC10537515
OpenAlexW4386285319

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.